TRIS-RO

Tris base

99.9% (titration), solid, abs., 100 mg/mL, 300 nm ≤0.015

• Synonym(s): Trizma^® base, amino-2-(hydroxymethyl)-1,3-propanediol, 2-, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Tris(hydroxymethyl)aminomethane, Trometamol
• Linear Formula: NH₂C(CH₂OH)₃
• CAS Number: 77-86-1
• Molecular Weight: 121.14
• Beilstein/REAXYS Number: 741883
• MDL number: MFCD00004679
• UNSPSC Code: 12161705
• PubChem Substance ID: 329827583

Properties

• product name: Tris base, =99.9% (titration), abs., 100 mg/mL, 300 nm ≤0.015
• description: aminopeptidase substrate
• assay: 99.9% (titration)
• packaging: pkg of 1 kg (10708976001); pkg of 5 kg (11814273001)
• manufacturer/tradename: Roche
• useful pH range: 7-9
• pKa (25 °C): 8.1
• bp: 219-220 °C/10 mmHg (lit.)
• mp: 167-172 °C (lit.)
• absorption: ≤0.015 at 300 nm at 100 mg/mL
• storage temp.: 20-25°C
• SMILES string: NC(CO)(CO)CO
• InChI: 1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
• InChI key: LENZDBCJOHFCAS-UHFFFAOYSA-N

Description

Quality

Contaminants: <0.001% PK and aldolase, each, <0.01% GOT, GPT, MDH and myokinase, each

Other Notes

For life science research only. Not for use in diagnostic procedures.

The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.
For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable