288306

Chloroform

anhydrous, ≥99%, contains 0.5-1.0% ethanol as stabilizer

• Synonym(s): Methylidyne trichloride, Trichloromethane
• Empirical Formula (Hill Notation): CHCl₃
• CAS Number: 67-66-3
• Molecular Weight: 119.38
• Beilstein/REAXYS Number: 1731042
• MDL number: MFCD00000826
• UNSPSC Code: 12191502
• PubChem Substance ID: 57648332
• NACRES: NA.21

Properties

• grade: anhydrous
• Quality Level: 100
• vapor density: 4.1 (vs air)
• vapor pressure: 160 mmHg ( 20 °C)
• assay: ≥99%
• form: liquid
• contains: 0.5-1.0% ethanol as stabilizer
• packaging: Sure/Seal^™ of 1, 2 L; Sure/Seal^™ of 100, 12x100 mL
• impurities: <0.001% water; <0.005% water (100 mL pkg)
• evapn. residue: <0.0003%
• color: colorless
• refractive index: n20/D 1.445 (lit.)
• bp: 60.5-61.5 °C (lit.)
• mp: −63 °C (lit.)
• density: 1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.)
• SMILES string: ClC(Cl)Cl
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• InChI key: HEDRZPFGACZZDS-UHFFFAOYSA-N

Description

General description

Chloroform is a volatile chlorinated organic solvent whose vapors have a narcotic effect. Due to its light sensitivity, it may undergo degradation with time. This can be suppressed by adding ethanol as a stabilizer. The addition will increase the polarity of the solvent and potentially impact certain applications.

Application

Chloroform has been used as a solvent for dissolving lipids and also as a cleansing agent. It may also be used in solvent extraction process and also for recrystallization.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372
• pcodes: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• target_organs: Central nervous system, Liver,Kidney
• wgk_germany: WGK 3