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390062

Sigma-Aldrich

Thiazole Orange

Dye content ~90 %

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Synonym(s):
1-Methyl-4-[(3-methyl-2(3H)-benzothiazolylidene)methyl]quinolinium p-tosylate
Empirical Formula (Hill Notation):
C26H24N2O3S2
CAS Number:
107091-89-4
Molecular Weight:
476.61
MDL number:
MFCD00192499
PubChem Substance ID:
24864313
NACRES:
NA.47

form

powder

Quality Level

200

composition

Dye content, ~90%

mp

270 °C (dec.) (lit.)

λmax

512 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Cc1ccc(cc1)S([O-])(=O)=O.CN2C(\Sc3ccccc23)=C\c4cc[n+](C)c5ccccc45

InChI

1S/C19H17N2S.C7H8O3S/c1-20-12-11-14(15-7-3-4-8-16(15)20)13-19-21(2)17-9-5-6-10-18(17)22-19;1-6-2-4-7(5-3-6)11(8,9)10/h3-13H,1-2H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1

InChI key

ACOJCCLIDPZYJC-UHFFFAOYSA-M

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1 of 4

This Item
114510O3756A6014
Thiazole Orange Dye content ~90 %

Sigma-Aldrich

390062

Thiazole Orange

Methyl Orange ACS reagent, Dye content 85 %

Sigma-Aldrich

114510

Methyl Orange

Orange G for NA electrophoresis

Sigma-Aldrich

O3756

Orange G

Acridine Orange hemi(zinc chloride) salt For nucleic acid staining in cells or gels

Sigma-Aldrich

A6014

Acridine Orange hemi(zinc chloride) salt

composition

Dye content, ~90%

composition

Dye content, 85%

composition

-

composition

Dye content, ~80%

mp

270 °C (dec.) (lit.)

mp

>300 °C

mp

-

mp

-

λmax

512 nm

λmax

505 nm

λmax

-

λmax

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

application(s)

-

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

General description

Thiazole Orange can be tethered with peptide nucleic acid for the detection of target nucleic acid in homogeneous solution. It is a dye with, both predicted physical characteristics and the biological staining characteristics of a good reticulocyte dye, hence it is considered as a dye for reticulocyte analysis. It has massive fluorescence enhancement and high quantum yield upon binding to nucleic acids, particularly RNA. It is non precipitating and can permeates through live cell membranes.

Application

Thiazole orange has been used for the staining and thereby quantification of reticulocytes.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315 - H319 - H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Light-up probes: thiazole orange-conjugated peptide nucleic acid for detection of target nucleic acid in homogeneous solution.
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