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D7008

Sigma-Aldrich

Dihydroethidium

≥95%

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Synonym(s):
2,7-Diamino-10-ethyl-9-phenyl-9,10-dihydrophenanthridine, 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine, Hydroethidine
Empirical Formula (Hill Notation):
C21H21N3
CAS Number:
Molecular Weight:
315.41
Beilstein/REAXYS Number:
5107482
MDL number:
PubChem Substance ID:
NACRES:
NA.47

Quality Level

assay

≥95%

form

powder

color

pink to very dark red

solubility

chloroform: 20 mg/mL

fluorescence

λex 370 nm; λem 420 nm (for cytoplasm of living cells)
λex 535 nm; λem 610 nm (for chromatin of living cells)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

CCN1C(c2ccccc2)c3cc(N)ccc3-c4ccc(N)cc14

InChI

1S/C21H21N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,21H,2,22-23H2,1H3

InChI key

XYJODUBPWNZLML-UHFFFAOYSA-N

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1 of 4

This Item
A8251861340A8126
Dihydroethidium ≥95%

D7008

Dihydroethidium

Acriflavine hydrochloride fluorescent dye

A8251

Acriflavine hydrochloride

Thionin acetate salt certified by the Biological Stain Commission, Dye content ≥85 %

861340

Thionin acetate salt

Acriflavine fluorescent label

A8126

Acriflavine

color

pink to very dark red

color

-

color

-

color

-

solubility

chloroform: 20 mg/mL

solubility

H2O: 1 mg/mL

solubility

-

solubility

H2O: 0.33 g/mL (lit.)(lit.)

form

powder

form

powder

form

powder

form

powder

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

assay

≥95%

assay

-

assay

-

assay

-

Application

Redox indicator. Blue fluorescence until oxidized to ethidium.
Dihydroethidium has been used as a superoxide probe in bovine pulmonary artery endothelial cell (BPAEC). It has been used to check the in situ generation of ROS (reactive oxygen species).

Packaging

Packaged under Argon.

Linkage

B-ring reduced analog of ethidium

related product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Articles

Oxidative stress is mediated, in part, by reactive oxygen species produced by multiple cellular processes and controlled by cellular antioxidant mechanisms such as enzymatic scavengers or antioxidant modulators. Free radicals, such as reactive oxygen species, cause cellular damage via cellular.

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