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A2646

Sigma-Aldrich

D-Arginine

≥98% (TLC)

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Synonym(s):
(R)-2-Amino-5-guanidinopentanoic acid
Linear Formula:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
CAS Number:
Molecular Weight:
174.20
Beilstein:
1725412
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.32

Assay

≥98% (TLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

mp

226 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

N[C@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m1/s1

InChI key

ODKSFYDXXFIFQN-SCSAIBSYSA-N

Gene Information

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This Item
S4250A5006A8094
D-Arginine ≥98% (TLC)

Sigma-Aldrich

A2646

D-Arginine

-
D-Serine ≥98% (TLC)

Sigma-Aldrich

S4250

D-Serine

-
L-Arginine reagent grade, ≥98%

Sigma-Aldrich

A5006

L-Arginine

Essential Grade
L-Arginine from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

A8094

L-Arginine

Premium Grade
form

powder

form

powder

form

powder

form

powder

technique(s)

ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

color

white to off-white

color

white to off-white

color

white

color

white

mp

226 °C (dec.) (lit.)

mp

-

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

General description

Arginine (Arg) is a dibasic amino acid and exists as two enantiomers: D-Arg and L-Arg. D-Arg is a cationic endogenous amino acid and is found in the central nervous system.

Application

D-Arginine has been used:
  • as an organic substrate to study the metabolic versatility of freshwater sedimentary archaea feeding on different organic carbon sources
  • to study its role in the inhibition of Pseudorabies virus (PRV) plaque formation by arginase
  • as a reference standard for chromatographic separation

Biochem/physiol Actions

D-Arginine is a semi-essential amino acid that maintains cell death in the central nervous system (CNS). It may possess neuroprotective actions against glucocorticoids induced neurotoxicity in the CNS.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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M Griselda Canteros
Drug discovery today, 19(5), 627-636 (2013-11-21)
In humans, as in other mammals, endogenous glucocorticoids (GCs) are essential for adapting to physiological life stress. They are also crucial for the healthy development of the fetus. However, when the physiological concentrations of GCs increase over a long period
Federica Lazzari et al.
Polymers, 12(4) (2020-04-17)
D- and L-arginine-based polyamidoamino acids, called D- and L-ARGO7, retain the chirality and acid/base properties of the parent -amino acids and show pH-dependent self-structuring in water. The ability of the ARGO7 chiral isomers to selectively interact with chiral biomolecules and/or
Bridget E Fomenky et al.
Scientific reports, 8(1), 14147-14147 (2018-09-22)
This study investigated the effect of supplementing the diet of calves with two direct fed microbials (DFMs) (Saccharomyces cerevisiae boulardii CNCM I-1079 (SCB) and Lactobacillus acidophilus BT1386 (LA)), and an antibiotic growth promoter (ATB). Thirty-two dairy calves were fed a
Gaëlle Coussot et al.
Astrobiology, 19(8), 1053-1062 (2019-03-01)
Antibody-based analytical instruments are under development to detect signatures of life on planetary bodies. Antibodies are molecular recognition reagents able to detect their target at sub-nanomolar concentrations, with high affinity and specificity. Studying antibody binding performances under space conditions is
Xiaobo Zhou et al.
Experimental cell research, 359(1), 195-204 (2017-07-29)
Preeclampsia(PE) is a pregnancy complication that is diagnosed by the new onset of hypertension and proteinuria. The etiology of PE remains unclear; however, growing evidence indicates that mitochondrial impairment contributes to the pathogenesis. Therefore, we aim to investigate the function

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