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A7631

Sigma-Aldrich

(+)-Sodium L-ascorbate

crystalline, ≥98%

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Synonym(s):
L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt
Empirical Formula (Hill Notation):
C6H7NaO6
CAS Number:
Molecular Weight:
198.11
Beilstein/REAXYS Number:
3767246
EC Number:
MDL number:
eCl@ss:
34058010
PubChem Substance ID:
NACRES:
NA.79

biological source

synthetic

Quality Level

assay

≥98%

form

crystalline

technique(s)

HPLC: suitable

color

white to off-white

mp

220 °C (dec.) (lit.)

SMILES string

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

InChI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1

InChI key

PPASLZSBLFJQEF-RXSVEWSESA-M

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This Item
A403411140PHR1279
(+)-Sodium L-ascorbate crystalline, ≥98%

A7631

(+)-Sodium L-ascorbate

-
(+)-Sodium L-ascorbate powder, BioReagent, suitable for cell culture

A4034

(+)-Sodium L-ascorbate

-
(+)-Sodium L-ascorbate BioXtra, ≥99.0% (NT)

11140

(+)-Sodium L-ascorbate

Premium Grade
Sodium ascorbate Pharmaceutical Secondary Standard; Certified Reference Material

PHR1279

Sodium ascorbate

-
biological source

synthetic

biological source

synthetic (organic)

biological source

fermentation/recombinant

biological source

-

assay

≥98%

assay

≥98%

assay

≥99.0% (NT)

assay

-

form

crystalline

form

powder

form

powder or crystals

form

-

color

white to off-white

color

white to off-white

color

white

color

-

mp

220 °C (dec.) (lit.)

mp

220 °C (dec.) (lit.)

mp

220 °C (dec.) (lit.)

mp

220 °C (dec.) (lit.)

General description

Ascorbic acid, also known as vitamin C, is a water-soluble vitamin. L-Ascorbic acid is a reducing agent.

Application

(+)-Sodium L-ascorbate has been used:
  • as a component of cutting solution for storing brain slices of rats
  • as a component of patch pipette internal solution for imaging Ca2+ transients evoked by action potential in rat brain slices
  • as a supplement for arterial smooth muscle cell (SMC) cultures to encourage collagen production

Biochem/physiol Actions

Ascorbic acid exhibits anti-oxidant properties. It is a primary substrate for detoxifying hydrogen peroxide. Ascorbic acid is a co-factor for the synthesis of adrenal steroids and catecholamines. L-Ascorbic acid (Vitamin C) is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress. L-Ascorbate can be regenerated by biological systems.

Caution

May darken in storage.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)


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Exogenous ascorbic acid (vitamin C) increases resistance to salt stress and reduces lipid peroxidation
Shalata A and Neumann P M
Journal of Experimental Botany, 52(364), 2207-2211 (2001)
Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla
Patak P, et al.
Endocrine Research, 30(4), 871-875 (2004)
Imaging calcium concentration dynamics in small neuronal compartments
Yasuda R, et al.
Science's STKE : Signal Transduction Knowledge Environment, 219, pl5-pl5 (2004)
Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice
Suen RS, et al.
The American Journal of Pathology, 179(3), 1549-1559 (2011)
Jiali Zhang et al.
Chemical communications (Cambridge, England), 46(7), 1112-1114 (2010-02-04)
We demonstrated that the individual graphene oxide sheets can be readily reduced under a mild condition using L-ascorbic acid (L-AA). This simple approach should find practical applications in large scale production of water soluble graphene.

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Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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