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A9256

Sigma-Aldrich

L-Aspartic acid

reagent grade, ≥98% (HPLC)

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Synonym(s):
(S)-(+)-Aminosuccinic acid, (S)-Aminobutanedioic acid
Linear Formula:
HO2CCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
133.10
Beilstein:
1723530
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

grade

reagent grade

Quality Level

Assay

≥98% (HPLC)

form

powder, crystals or chunks

color

white to off-white

mp

>300 °C (dec.) (lit.)

solubility

H2O: 5 mg/mL
0.5 M HCl: 50 mg/mL (with heat)
1 M NaOH: 50 mg/mL

SMILES string

N[C@@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key

CKLJMWTZIZZHCS-REOHCLBHSA-N

Gene Information

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This Item
A8949PHL80666A7219
L-Aspartic acid reagent grade, ≥98% (HPLC)

Sigma-Aldrich

A9256

L-Aspartic acid

Essential Grade
L-Aspartic acid BioXtra, ≥99% (HPLC)

Sigma-Aldrich

A8949

L-Aspartic acid

Premium Grade
L-Aspartic acid phyproof® Reference Substance

PHL80666

L-Aspartic acid

-
L-Aspartic acid from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

A7219

L-Aspartic acid

-
assay

≥98% (HPLC)

assay

≥99% (HPLC)

assay

≥98.0% (HPLC)

assay

98.5-101.0%

form

powder, crystals or chunks

form

powder

form

powder

form

powder

color

white to off-white

color

white to off-white

color

-

color

white to off-white

mp

>300 °C (dec.) (lit.)

mp

>300 °C (dec.) (lit.)

mp

>300 °C (dec.) (lit.)

mp

>300 °C (dec.) (lit.)

solubility

H2O: 5 mg/mL, 0.5 M HCl: 50 mg/mL (with heat), 1 M NaOH: 50 mg/mL

solubility

1 M HCl: 0.5 M, clear, colorless

solubility

-

solubility

1 M HCl: 100 mg/mL

Application

L-aspartic acid has been used as one of the components of synthetic drop out media for culturing budding yeast. It has also been used to study non-enzymatic gluconeogenesis.

Biochem/physiol Actions

Principal neurotransmitter for fast synaptic excitation.
Aspartic acid is a non-essential amino acid. It is involved in the Urea cycle, Krebs cycle and in DNA metabolism.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Eric R. Braverman
The Healing Nutrients Within: Facts, Findings, and New Research on Amino Acids, 1-504 (2007)
Method for Multiplexing CRISPR/Cas9 in Saccharomyces cerevisiae Using Artificial Target DNA Sequences
Rachael M. Giersch and Gregory C. Finnigan
Bio-protocol, 7(18), 1-24 (2017)
Nonenzymatic gluconeogenesis-like formation of fructose 1,6-bisphosphate in ice.
Messner CB
Proceedings of the National Academy of Sciences of the USA, 114(28), 7403-7407 (2017)
Jorge S Valadas et al.
Neuron, 98(6), 1155-1169 (2018-06-12)
Parkinson's disease patients report disturbed sleep patterns long before motor dysfunction. Here, in parkin and pink1 models, we identify circadian rhythm and sleep pattern defects and map these to specific neuropeptidergic neurons in fly models and in hypothalamic neurons differentiated
Eran Mick et al.
eLife, 9 (2020-05-29)
Mitochondrial dysfunction is associated with activation of the integrated stress response (ISR) but the underlying triggers remain unclear. We systematically combined acute mitochondrial inhibitors with genetic tools for compartment-specific NADH oxidation to trace mechanisms linking different forms of mitochondrial dysfunction

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