C4042
Captopril
≥98% (HPLC), powder, angiotensin converting enzyme inhibitor
Synonym(s):
N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline
About This Item
Recommended Products
product name
Captopril, ≥98% (HPLC), powder
biological source
synthetic
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to off-white
mp
104-108 °C (lit.)
solubility
water: 100 mg/mL, clear to very slightly hazy, colorless to faintly yellow
originator
Bristol-Myers Squibb
storage temp.
room temp
SMILES string
C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O
InChI
1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1
InChI key
FAKRSMQSSFJEIM-RQJHMYQMSA-N
Gene Information
human ... ACE(1636) , AGTR1(185) , AGTR2(186) , ECE1(1889)
rat ... Ace(24310)
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Application
- to examine the influence of timing of captopril treatment on efficacy in transverse aortic constriction (TAC) mice
- as an angiotensin-converting enzyme inhibitor and orally administered to unrestrained Wistar Kyoto rats in an approach to study its effects of angiogenesis inhibition and interdependency with other drugs
- used as a positive control in spectrophotometric assay to study the angiotensin-converting enzyme inhibitory activity
Biochem/physiol Actions
Features and Benefits
signalword
Danger
hcodes
Hazard Classifications
Muta. 2 - Repr. 1B
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Certificates of Analysis (COA)
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