D153

(R)(−)-DOI hydrochloride

≥98% (HPLC), solid

• Synonym(s): (−)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride, (−)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride
• Empirical Formula (Hill Notation): C₁₁H₁₆INO₂ · HCl
• CAS Number: 82864-02-6
• Molecular Weight: 357.62
• MDL number: MFCD00153796
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278404
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• optical activity: [α]22/D −12.36°, c = 2 in H₂O(lit.)
• drug control: Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada
• color: white
• solubility: H₂O: ≥20 mg/mL; ethanol: soluble
• SMILES string: Cl.COc1cc(C[C@@H](C)N)c(OC)cc1I
• InChI: 1S/C11H16INO2.ClH/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2;/h5-7H,4,13H2,1-3H3;1H/t7-;/m1./s1
• InChI key: QVFDMWGKHUFODK-OGFXRTJISA-N
• Gene Information: human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)

Description

Biochem/physiol Actions

Potent and selective 5-HT₂ serotonin receptor agonist that crosses the blood-brain barrier; more potent enantiomer of ±-DOI hydrochloride.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)