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Key Documents

D9753

Sigma-Aldrich

DL-3,4-Dihydroxyphenyl glycol

Synonym(s):

DL-α,β,3,4-Tetrahydroxyphenethyl alcohol, DL-β,3,4-Trihydroxyphenethyl alcohol

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About This Item

Empirical Formula (Hill Notation):
C8H10O4
CAS Number:
Molecular Weight:
170.16
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.25

form

powder

Quality Level

storage temp.

−20°C

SMILES string

OCC(O)c1ccc(O)c(O)c1

InChI

1S/C8H10O4/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8-12H,4H2

InChI key

MTVWFVDWRVYDOR-UHFFFAOYSA-N

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Graeme Eisenhofer et al.
Pharmacological reviews, 56(3), 331-349 (2004-08-20)
This article provides an update about catecholamine metabolism, with emphasis on correcting common misconceptions relevant to catecholamine systems in health and disease. Importantly, most metabolism of catecholamines takes place within the same cells where the amines are synthesized. This mainly
Osnat Ben-Shahar et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(2), 495-506a-495-506a (2013-01-11)
Anomalies in prefrontal cortex (PFC) function are posited to underpin difficulties in learning to suppress drug-seeking behavior during abstinence. Because group 1 metabotropic glutamate receptors (mGluRs) regulate drug-related learning, we assayed the consequences of extended access to intravenous cocaine (6
David S Goldstein et al.
Brain : a journal of neurology, 135(Pt 6), 1900-1913 (2012-03-28)
Central catecholamine deficiency characterizes α-synucleinopathies such as Parkinson's disease. We hypothesized that cerebrospinal fluid levels of neuronal metabolites of catecholamines provide neurochemical biomarkers of these disorders. To test this hypothesis we measured cerebrospinal fluid levels of catechols including dopamine, norepinephrine
Adrianne R Wilson-Poe et al.
Neuropharmacology, 66, 348-354 (2012-07-10)
Metabotropic glutamate (mGlu) receptors modulate pain from within the midbrain periaqueductal grey (PAG). In the present study, the postsynaptic mGlu receptor mediated effects on rat PAG neurons were examined using whole-cell patch-clamp recordings in brain slices. The selective group I
G Eisenhofer et al.
The Journal of clinical endocrinology and metabolism, 68(2), 247-255 (1989-02-01)
Dihydroxyphenylalanine (DOPA) is the immediate product of the rate-limiting step in catecholamine biosynthesis, hydroxylation of tyrosine. This study examined whether plasma concentrations of DOPA are related to tyrosine hydroxylase activity. Plasma concentrations of DOPA, norepinephrine, and the norepinephrine metabolites 3,4-dihydroxyphenylglycol

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