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G4501

Sigma-Aldrich

L-Glutathione oxidized

≥98%, lyophilized powder

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Synonym(s):
GSSG, Glutathiol
Empirical Formula (Hill Notation):
C20H32N6O12S2
CAS Number:
Molecular Weight:
612.63
Beilstein:
1718700
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

Assay

≥98%

form

lyophilized powder

impurities

Ethanol, free

color

white

solubility

H2O: 50 mg/mL, clear, colorless

application(s)

detection

storage temp.

2-8°C

SMILES string

N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1

InChI key

YPZRWBKMTBYPTK-BJDJZHNGSA-N

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1 of 4

This Item
G6654G43763542
L-Glutathione oxidized ≥98%, lyophilized powder

Sigma-Aldrich

G4501

L-Glutathione oxidized

-
L-Glutathione oxidized BioXtra, ≥98%

Sigma-Aldrich

G6654

L-Glutathione oxidized

Premium Grade
L-Glutathione oxidized ≥98% (HPLC)

Sigma-Aldrich

G4376

L-Glutathione oxidized

-
form

lyophilized powder

form

powder

form

powder

form

solid

impurities

Ethanol, free

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter, ≤6% ethanol

impurities

-

impurities

-

color

white

color

white

color

-

color

white

solubility

H2O: 50 mg/mL, clear, colorless

solubility

H2O: 0.1 M at 20 °C, clear, colorless

solubility

H2O: soluble

solubility

water: 1 mg/mL, DMF: 10 mg/mL, ethanol: 5 mg/mL

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Amino Acid Sequence

Glu-Cys-Gly, Glu-Cys-Gly [Disulfide bridge: 2a-2b]

Biochem/physiol Actions

L-Glutathione, oxidized is frequently measure in vivo as an indicator of oxidative stress. Oxidized L-Glutathione may be converted to L-glutathione by various reducing systems.

related product

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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N O Kaakoush et al.
Antimicrobial agents and chemotherapy, 53(5), 1884-1891 (2009-02-19)
Metronidazole resistance in Helicobacter pylori has been attributed to mutations in rdxA or frxA. Insufficient data correlating RdxA and/or FrxA with the resistant phenotype, and the emergence of resistant strains with no mutations in either rdxA or frxA, indicated that
S K Tandon et al.
Toxicology letters, 145(3), 211-217 (2003-10-29)
The influence of an antioxidant agent such as N-acetyl cysteine (NAC) or mannitol on the cadmium chelating ability of monoisoamyl 2,3-dimercaptosuccinate (MiADMS) was investigated in cadmium pre-exposed rats. This ester of 2,3-dimercaptosuccinic acid (DMSA), an accepted drug for lead poisoning
Roman Kireev et al.
European journal of pharmacology, 701(1-3), 185-193 (2012-12-12)
Fatty livers occur in up to 20% of potential liver donors and increase cellular injury during the ischemia/reperfusion phase, so any intervention that could enable a better outcome of grafts for liver transplantation would be very useful. The effect of
T Kondo et al.
American journal of hematology, 26(1), 37-45 (1987-09-01)
The oxidized form of glutathione transport was studied in human erythrocytes in pyrimidine 5'-nucleotidase (P5N) deficiency, a disorder in which the amounts of CTP and UTP in the erythrocytes are elevated. The inhibition of ATP-requiring oxidized glutathione (GSSG) transport by
P Aukrust et al.
Blood, 86(1), 258-267 (1995-07-01)
We investigated the intracellular glutathione redox status in isolated lymphocyte subpopulations and monocytes in patients with human immunodeficiency virus type 1 (HIV-1) infection and in healthy controls. CD4+ lymphocytes from HIV-1-infected patients were primarily characterized by a substantial increase in

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