H6269

Hexadecyltrimethylammonium bromide

for molecular biology, ≥99%

• Synonym(s): CTAB, Cetrimonium bromide, Cetyltrimethylammonium bromide, Palmityltrimethylammonium bromide
• Linear Formula: CH₃(CH₂)₁₅N(Br)(CH₃)₃
• CAS Number: 57-09-0
• Molecular Weight: 364.45
• Beilstein/REAXYS Number: 3598189
• EC Number: 200-311-3
• MDL number: MFCD00011772
• UNSPSC Code: 12161902
• PubChem Substance ID: 24895734
• NACRES: NA.31

Properties

• grade: for molecular biology
• description: cationic
• assay: ≥99%
• form: powder or crystals
• mol wt: micellar avg mol wt 62,000
• aggregation number: 170
• pH: 5.0-7 (25 °C, 36.4 g/L)
• CMC: 0.92; 1 mM (20-25°C)
• mp: 248-251 °C (lit.)
• solubility: H₂O: 1/10 g/mL
• HLB: 10
• suitability: suitable for DNA precipitation
• foreign activity: DNAse (Detection); NICKase Detection ; RNAse, none detected
• SMILES string: [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C
• InChI: 1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1
• InChI key: LZZYPRNAOMGNLH-UHFFFAOYSA-M

Description

Application

Hexadecyltrimethylammonium bromide has been used:

• as a component of DNA extraction buffer and RNA extraction buffer
• as a constituent of dye dissolution buffer

Biochem/physiol Actions

Hexadecyltrimethylammonium bromide also called cetyltrimethylammonium bromide (CTAB), is a cationic surfactant. CTAB method is an efficient, cost and time effective method of DNA extraction.

Safety Information

• pictograms: GHS08,GHS05,GHS07,GHS09
• signalword: Danger
• hcodes: H302,H315,H318,H335,H373,H410
• pcodes: P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT RE 2 Oral - STOT SE 3
• target_organs: Gastrointestinal tract, Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: 471.2 °F - closed cup
• flash_point_c: 244 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves