MilliporeSigma
All Photos(1)

P8908

Sigma-Aldrich

Prostaglandin E1

synthetic, powder, BioReagent, suitable for cell culture

Sign Into View Organizational & Contract Pricing

Select a Size

Synonym(s):
(11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid, Alprostadil, PGE1
Empirical Formula (Hill Notation):
C20H34O5
CAS Number:
Molecular Weight:
354.48
Beilstein:
5294062
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

biological source

synthetic

Quality Level

product line

BioReagent

Assay

≥98% (HPLC)

form

powder

potency

0.25-100 ng/mL

technique(s)

cell culture | mammalian: suitable

solubility

acetone: 10 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1

InChI

1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

InChI key

GMVPRGQOIOIIMI-DWKJAMRDSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
P7527P5515538903
Prostaglandin E1 synthetic, powder, BioReagent, suitable for cell culture

Sigma-Aldrich

P8908

Prostaglandin E1

Prostaglandin E1 powder, γ-irradiated, BioXtra, suitable for cell culture

Sigma-Aldrich

P7527

Prostaglandin E1

Prostaglandin E1 ≥98% (HPLC), synthetic

Sigma-Aldrich

P5515

Prostaglandin E1

Prostaglandin E1 Activates adenylate cyclase activity via a G-protein coupled receptor.

Millipore

538903

Prostaglandin E1

product line

BioReagent

product line

BioXtra

product line

-

product line

-

assay

≥98% (HPLC)

assay

-

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

(powder to crystals)

form

solid

potency

0.25-100 ng/mL

potency

-

potency

-

potency

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

General description

Prostaglandin E1 (PGE1) is a vasodilator.

Application

Prostaglandin E1 may be used in cell culture to protect human umbilical vein endothelial cells (HUVEC) from injury induced by hydrogen peroxide.

Biochem/physiol Actions

Prostaglandin E1 (PGE1) aids in the relaxation of corporal cavernosal tissue. It helps to preserve the patency of the ductus arteriosus. It is used to treat erectile dysfunction (ED).

Physical form

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 9

1 of 9

Vasculogenic Erectile Dysfunction
Vascular Medicine: A Companion to Braunwald's Heart Disease, 341-348 (2013)
Cardiac Physiology and Pharmacology
A Practice of Anesthesia for Infants and Children, 424-457 (2019)
Corticotrophins, corticosteroids, and prostaglandins
Side Effects of Drugs Annual, 32, 723-733 (2010)
Prostaglandin E1 for treatment of erectile dysfunction
Urciuoli R, et al.
Cochrane database of systematic reviews (Online), Cochrane(Database), Syst-Syst (2004)
David Furman et al.
Nature medicine, 23(2), 174-184 (2017-01-17)
Low-grade, chronic inflammation has been associated with many diseases of aging, but the mechanisms responsible for producing this inflammation remain unclear. Inflammasomes can drive chronic inflammation in the context of an infectious disease or cellular stress, and they trigger the

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service