1392705

Mesalamine

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 5-Aminosalicylic acid, 5-AS, 5-Amino-2-hydroxybenzoic acid, Mesalamine
• Linear Formula: H₂NC₆H₃-2-(OH)CO₂H
• CAS Number: 89-57-6
• Molecular Weight: 153.14
• Beilstein/REAXYS Number: 2090421
• MDL number: MFCD00007877
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750370
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: mesalamine, mesalazine
• manufacturer/tradename: USP
• mp: 275-280 °C (dec.) (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: Nc1ccc(O)c(c1)C(O)=O
• InChI: 1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)
• InChI key: KBOPZPXVLCULAV-UHFFFAOYSA-N
• Gene Information: human ... ALOX5(240) , PPARG(5468) , PTGS1(5742) , PTGS2(5743)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Mesalamine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Mesalamine Delayed-Release Tablets
• Mesalamine Extended-Release Capsules
• Mesalamine Rectal Suspension

5-Aminosalicylic acid is a peroxidase substrate suitable for use in ELISA procedures. This substrate produces a soluble end product that is brown in color and can be read spectrophotometrically at 450 nm. The reaction may be stopped with 3 N NaOH and read at 550 nm.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H317,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: No data available
• flash_point_c: No data available