ACE

angiotensin I converting enzyme

Synonyms:

ACE1, CD143, DCP, DCP1, ICH, MVCD3

Species:

Human ACE (1636), Mouse Ace (11421), Rat Ace (24310), fruit fly Ace (41625), Zebrafish ace (565980), chicken ACE (419953), dog ACE (610668), Horse ACE (100064801), cow ACE (509484), sheep ACE (554335)

UniProtKB ID:

P12821, B0LPF0, B4DXI3, E7EU16, P22966, Q53YX9, Q59GY8, Q7M4L4

Gene ID:

Human(1636) Summary: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
Mouse(11421) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Rat(24310) angiotensin I converting enzyme
fruit fly(41625) Acetylcholine esterase
Zebrafish(565980) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chicken(419953) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
dog(610668) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Horse(100064801) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
cow(509484) angiotensin I converting enzyme
sheep(554335) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Domestic Rabbit(100009274) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

Products (67)
Peer Reviewed Papers (4,227)

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ELISA

Product Number

Description

Species

RAB1243

Human ACE ELISA, for serum, plasma and cell culture supernatants,

Species

human

RAB0002

Mouse ACE ELISA Kit, for serum, plasma and cell culture supernatant,

Species

mouse

Antibodies

Product Number

Description

Species Reactivity

Application

ZRB2821

Anti-ACE Antibody, clone 1E15 ZooMAb^® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,

Species Reactivity

human, monkey, rat

Application

affinity binding assay
immunofluorescence
immunohistochemistry
western blot

HPA029298

Anti-ACE antibody produced in rabbit, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,

Species Reactivity

human

Application

immunohistochemistry
western blot

SAB4301112

Anti-ACE1 antibody produced in rabbit, affinity isolated antibody,

Species Reactivity

human, mouse

Application

western blot

HPA069790

Anti-ACE antibody produced in rabbit, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody,