ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
Synonyms:
Species:
Human ATP1A1 (476), Mouse Atp1a1 (11928), Rat Atp1a1 (24211), domestic cat ATP1A1 (101083695), Horse ATP1A1 (100034139), dog ATP1A1 (403992), chicken ATP1A1 (396530), Domestic Rabbit ATP1A1 (100302415), sheep ATP1A1 (443381), cow ATP1A1 (282144) ...More
UniProtKB ID:
Gene ID:
- Human(476) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
- Mouse(11928) ATPase, Na+/K+ transporting, alpha 1 polypeptide
- Rat(24211) ATPase, Na+/K+ transporting, alpha 1 polypeptide
- domestic cat(101083695) ATPase, Na+/K+ transporting, alpha 1 polypeptide
- Horse(100034139) ATPase, Na+/K+ transporting, alpha 1 polypeptide
- dog(403992) ATPase, Na+/K+ transporting, alpha 1 polypeptide
- chicken(396530) ATPase, Na+/K+ transporting, alpha 1 polypeptide
- Domestic Rabbit(100302415) ATPase, Na+/K+ transporting, alpha 1 polypeptide
- sheep(443381) ATPase, Na+/K+ transporting, alpha 1 polypeptide
- cow(282144) ATPase, Na+/K+ transporting, alpha 1 polypeptide
- naked mole-rat(101697634) ATPase, Na+/K+ transporting, alpha 1 polypeptide
- domestic guinea pig(100192382) ATPase, Na+/K+ transporting, alpha 1 polypeptide
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Small Molecule - Activator
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Phospho-ATP1A1-S16 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Na+/K+ ATPase alpha-3, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-ATP1A1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-ATPASE antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-phospho-ATP1 α1/Na+K+ ATPase1 (pSer23) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Digoxin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Proteins
Product Number
Description
Species
Adenosine 5′-Triphosphatase from porcine cerebral cortex, lyophilized powder, ≥0.3 units/mg protein, pH 7.8,
Species