D6003

Digoxin

analytical standard

• Synonym(s): 12β-Hydroxydigitoxin
• Empirical Formula (Hill Notation): C₄₁H₆₄O₁₄
• CAS Number: 20830-75-5
• Molecular Weight: 780.94
• Beilstein/REAXYS Number: 77011
• EC Number: 244-068-1
• MDL number: MFCD00003674
• UNSPSC Code: 41116107
• PubChem Substance ID: 329798818
• NACRES: NA.24

Properties

• biological source: plant (Digitalis lanata)
• Quality Level: 100
• grade: analytical standard
• assay: ≥95.0% (HPLC)
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• solubility: methanol: methylene chloride (1:1): 0.5%, clear, colorless
• application(s): food and beverages; forensics and toxicology; veterinary
• format: neat
• functional group: ketone
• shipped in: ambient

Description

Application

Digoxin may be used as an analytical reference standard for the quantification of the analyte in biological samples[1][2] using chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

A cardiac glycoside, substrate for Pgp, upregulates Pgp expression and down regulates SXR (Steroid Xenobiotic Receptor).

A cardiac glycoside, substrate for Pgp.

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H300,H331,H373
• pcodes: P260 - P264 - P271 - P301 + P310 - P304 + P340 + P311 - P314
• Hazard Classifications: Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges