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ATP1A3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

Synonyms:
AHC2, DYT12, RDP
Species:
UniProtKB ID:
Gene ID:
  • Human(478) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(232975) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • Rat(24213) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • domestic cat(101083636) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • Horse(100069796) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • dog(612463) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • chicken(396467) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • naked mole-rat(101721146) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • cow(282598) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • sheep(101103751) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • domestic guinea pig(100712985) ATPase, Na+/K+ transporting, alpha 3 polypeptide

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ATP1A3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Na+/K+ ATPase β-1 Antibody, clone C464.8, clone C464.8, Upstate®, from mouse,
Species Reactivity
bovine, canine, human, rabbit, rat
Application
immunohistochemistry
western blot
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, clone C464.6, Upstate®, from mouse,
Species Reactivity
xenopus, canine, human, monkey, mouse, pig, rabbit, rat, sheep
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-ATP1A3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor 555, clone C464.6, Upstate®, from mouse,
Species Reactivity
xenopus, canine, human, monkey, mouse, pig, rabbit, rat, sheep
Application
flow cytometry
immunofluorescence

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Digoxin, analytical standard,
Species
human
Digoxin, United States Pharmacopeia (USP) Reference Standard,
Species
human
Digitoxin for LC assay, European Pharmacopoeia (EP) Reference Standard,
Species
human
Digoxin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Digoxin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ATP1A3,
Species
human
MISSION® esiRNA, targeting mouse Atp1a3,
Species
mouse