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ATP1B3

ATPase, Na+/K+ transporting, beta 3 polypeptide

Synonyms:
ATPB-3, CD298
Species:
UniProtKB ID:
Gene ID:
  • Human(483) Summary: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008]
  • Mouse(11933) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • Rat(25390) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • domestic cat(101097586) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • Horse(100062895) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • cow(532844) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • chicken(396549) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • dog(477098) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • domestic guinea pig(100135484) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • naked mole-rat(101697891) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • Domestic Rabbit(100008788) ATPase, Na+/K+ transporting, beta 3 polypeptide

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ATP1B3 antibody produced in mouse, clone 1E9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-ATP1B3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, rat
Application
western blot
Anti-ATP1B3 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-ATP1B3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-ATP1B3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Digitoxin, ≥92% (HPLC), powder,
Species
human
Digoxin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Digitoxin, British Pharmacopoeia (BP) Reference Standard,
Species
human
Digitoxin, phyproof® Reference Substance,
Species
human
Digitoxin, European Pharmacopoeia (EP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ATP1B3,
Species
human
MISSION® esiRNA, targeting mouse Atp1b3,
Species
mouse