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DRD5

dopamine receptor D5

Synonyms:

DBDR, DRD1B, DRD1L2

Species:

Human DRD5 (1816), Mouse Drd5 (13492), Rat Drd5 (25195), dog DRD5 (488824), domestic cat DRD5 (101091278), domestic guinea pig Drd5 (100732538), naked mole-rat Drd5 (101716828), chicken DRD5 (428795), Domestic Rabbit DRD5 (100342687), sheep DRD5 (101114778)

UniProtKB ID:

P21918, B2R9S3, Q8NEQ8

Gene ID:

Human(1816) Summary: This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008]
Mouse(13492) dopamine receptor D5
Rat(25195) dopamine receptor D5
dog(488824) dopamine receptor D5
domestic cat(101091278) dopamine receptor D5
domestic guinea pig(100732538) dopamine receptor D5
naked mole-rat(101716828) dopamine receptor D5
chicken(428795) dopamine receptor D5
Domestic Rabbit(100342687) dopamine receptor D5
sheep(101114778) dopamine receptor D5
cow(526221) dopamine receptor D5

Products (34)
Peer Reviewed Papers (78)

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Small Molecule - Agonist

Product Number

Description

Species

R-(−)-Apomorphine hydrochloride hemihydrate, calcined, ≥98% (with NaOH, titration),

Species

human

Pergolide mesylate, United States Pharmacopeia (USP) Reference Standard,

Species

human

Memantine hydrochloride, ≥98% (GC),

Species

human

Pergolide mesilate, European Pharmacopoeia (EP) Reference Standard,

Species

human

Small Molecule - Antagonist

Product Number

Description

Species

T103

Trifluperidol hydrochloride, ,

Species

human

F114

cis-(Z)-Flupenthixol dihydrochloride, ≥98% (HPLC), solid,

Species

human

F100

Fluspirilene, ,

Species

human

Pimozide, British Pharmacopoeia (BP) Reference Standard,

Species

human

Pimozide, United States Pharmacopeia (USP) Reference Standard,

Species

human

Antibodies

Product Number

Description

Species Reactivity

Application

Anti-Dopamine D₅ Receptor Rabbit pAb, lyophilized, Calbiochem^®,

Species Reactivity

human, rat

Application

Anti-DRD5 / DOPAMINE antibody produced in rabbit, affinity isolated antibody,

Species Reactivity

human, rat

Application

immunohistochemistry

Small Molecule - Inhibitor

Product Number

Description

Species

D052

GBR 12909 dihydrochloride, solid, ≥98% (HPLC),

Species

human

B102

Bupropion hydrochloride, ≥98% (HPLC), solid,

Species

human

Amoxapine, Pharmaceutical Secondary Standard; Certified Reference Material,

Species

human

Amoxapine, United States Pharmacopeia (USP) Reference Standard,

Species

human

Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant^®,

Species

human

Small Molecule - Metabolite

Product Number

Description

Species

3-Hydroxy-4-methoxyphenethylamine hydrochloride, ,

Species

human

3-Methoxytyramine hydrochloride, ≥95.5%, crystalline,

Species

human

Small Molecule - Precursor

Product Number

Description

Species

3,4-Dihydroxy-DL-phenylalanine, ,

Species

mouse, human, rat

3,4-Dihydroxy-L-phenylalanine, ≥98% (TLC),

Species

mouse, human, rat

esiRNA

Product Number

Description

Species

MISSION^® esiRNA, targeting human DRD5,

Species

human