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Merck

GTF2A2

general transcription factor IIA, 2, 12kDa

Sinonimi:
HsT18745, TF2A2, TFIIA
Specie:
ID UniProtKB:
ID gene:
  • Human(2958) Summary: Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]
  • Mouse(235459) general transcription factor II A, 2
  • Rat(83828) general transcription factor IIA, 2
  • sheep(101114960) general transcription factor IIA, 2, 12kDa
  • dog(478327) general transcription factor IIA, 2, 12kDa
  • chicken(770910) general transcription factor IIA, 2, 12kDa
  • domestic guinea pig(100716605) general transcription factor IIA, 2, 12kDa
  • Zebrafish(798997) general transcription factor IIA, 2
  • cow(613479) general transcription factor IIA, 2, 12kDa
  • domestic cat(101100892) general transcription factor IIA, 2, 12kDa
  • naked mole-rat(101725193) general transcription factor IIA, 2, 12kDa

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-GTF2A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
ChIP
immunofluorescence

western blot
Monoclonal Anti-GTF2A2 antibody produced in mouse, clone 2B9, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot

Proteins

Numero di prodotto
Descrizione
Specie
TFIIA (p12), γ subunit, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Specie
human
TFIIA-p12 human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Specie
human
TFIIA, reconstituted human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human GTF2A2,
Specie
human