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Merck

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Synonyma:
C-Kit, CD117, PBT, SCFR
Druh:
ID sady UniProtKB:
ID genu:
  • Human(3815) Summary: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(16590) kit oncogene
  • Rat(64030) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Domestic Rabbit(100327263) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • dog(403811) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic cat(493766) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Horse(100009704) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • cow(280832) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Goat(100861386) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • sheep(780504) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • chicken(378783) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic guinea pig(100726397) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • naked mole-rat(101726400) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Custom & Knockdown Gene Products

ELISA

Číslo produktu
Popis
Druh
Human KIT / Mast/Stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Druh
human
Phosphotyrosine KIT / Mast/stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Druh
human

Antibodies

Číslo produktu
Popis
Druhová reaktivita
Aplikace
Anti-C-KIT antibody produced in rabbit, affinity isolated antibody,
Druhová reaktivita
human, mouse, rat
Aplikace
ELISA
western blot
Anti-KIT antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Druhová reaktivita
human
Aplikace
immunohistochemistry
Anti-phospho-KIT (pTyr721) antibody produced in rabbit, affinity isolated antibody,
Druhová reaktivita
human
Aplikace
western blot
Anti-phospho-KIT (pTyr703) antibody produced in rabbit, affinity isolated antibody,
Druhová reaktivita
human, mouse, rat
Aplikace
ELISA
immunohistochemistry

western blot
ANTI-KIT antibody produced in mouse, clone 1D3, purified immunoglobulin, buffered aqueous solution,
Druhová reaktivita
human
Aplikace
ELISA
western blot

Small Molecule - Inhibitor

Číslo produktu
Popis
Druh
Imatinib, ,
Druh
human
Pazopanib, ,
Druh
human
Dasatinib, ,
Druh
human
Dasatinib, ≥98% (HPLC),
Druh
human

Proteins

Číslo produktu
Popis
Druh
c-KIT (544-end, V654A), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Druh
human
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Druh
human
c-KIT (N822K), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Druh
human
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥22% (SDS-PAGE),
Druh
human
c-Kit (D816H) Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant, human c-Kit, amino acids 544-end containing the mutation D816H, for use in Kinase Assays.,
Druh
human

esiRNA

Číslo produktu
Popis
Druh
MISSION® esiRNA, targeting human KIT,
Druh
human
MISSION® esiRNA, targeting mouse Kit,
Druh
mouse