PRKCB
protein kinase C, beta
Synonyms:
PKC-beta, PKCB, PRKCB1, PRKCB2
Species:
Human PRKCB (5579), Mouse Prkcb (18751), Rat Prkcb (25023), Domestic Rabbit PRKCB (100037719), sheep PRKCB (101118410), naked mole-rat Prkcb (101722702), domestic cat PRKCB (101088970), chicken PRKCB (416567), dog PRKCB (489968), cow PRKCB (282325)
UniProtKB ID:
Gene ID:
- Human(5579) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(18751) protein kinase C, beta
- Rat(25023) protein kinase C, beta
- Domestic Rabbit(100037719) protein kinase C, beta
- sheep(101118410) protein kinase C, beta
- naked mole-rat(101722702) protein kinase C, beta
- domestic cat(101088970) protein kinase C, beta
- chicken(416567) protein kinase C, beta
- dog(489968) protein kinase C, beta
- cow(282325) protein kinase C, beta
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Small Molecule - Agonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
ANTI-PKC BETA1/2 (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-PKCβ Antibody, clone 2E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-p-PKCβ (Ser660) Antibody, clone 2C11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, human, monkey, mouse, rabbit, rat
Application
affinity binding assay
immunocytochemistry
inhibition assay
western blot
immunocytochemistry
inhibition assay
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
Protein kinase CβII isozyme human, >85% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Species
human