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SRC

v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

Synonyms:
ASV, SRC1, c-SRC, p60-Src
Species:
Human SRC (6714), Mouse Src (20779), Rat Src (83805), Zebrafish src (325084), chicken SRC (396442), domestic cat SRC (101100378), dog SRC (485864), sheep SRC (101103084), cow SRC (535742), domestic guinea pig Src (100728509)
UniProtKB ID:
P12931, E1P5V4, Q76P87, Q86VB9, Q9H5A8
Gene ID:
  • Human(6714) Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20779) Rous sarcoma oncogene
  • Rat(83805) v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • Zebrafish(325084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • chicken(396442) v-src sarcoma viral oncogene
  • domestic cat(101100378) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • dog(485864) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • sheep(101103084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • cow(535742) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic guinea pig(100728509) Rous sarcoma oncogene
  • naked mole-rat(101703827) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

Custom & Knockdown Gene Products

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Product Number
Description
Species
452289
Phosphoric acid, ≥85 wt. % in H2O, ≥99.999% trace metals basis,
Species
human
30417
Phosphoric acid, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥85%,
Species
human
27487
Citric acid, BioUltra, anhydrous, ≥99.5% (T),
Species
human
251275
Citric acid, ACS reagent, ≥99.5%,
Species
human
C2404
Citric acid, anhydrous, suitable for cell culture, suitable for plant cell culture,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB4504536
Anti-phospho-Src (pTyr418) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB5701860
Anti-Phospho-Src-Y419 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
07-909
Anti-phospho-Src (Tyr418) Antibody, Upstate®, from rabbit,
Species Reactivity
chicken, human, mouse
Application
immunocytochemistry
immunohistochemistry
western blot
05-185
Anti-avian Src Antibody, clone EC10, clone EC10, Upstate®, from mouse,
Species Reactivity
avian
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
04-772
Anti-Src Antibody, CT, clone NL19 | 04-772, clone NL19, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
S9692
SU 6656, ≥98% (HPLC),
Species
human
R2146
Radicicol from Diheterospora chlamydosporia, solid,
Species
human, rat
PZ0192
Bosutinib, ≥98% (HPLC),
Species
human
E2250
Ellagic acid, ≥95% (HPLC), powder, from tree bark,
Species
human, rat
T182
Tyrphostin A9, solid,
Species
mouse, human

Kits

Product Number
Description
Species
20-121
Src Kinase Reaction Buffer, ,
Species
human

Proteins

Product Number
Description
Species
S1076
SRC, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
S5564
SRC N1 human, ≥60% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Species
human
14-746M-M
Src (1-530) Protein, active, 250 µg, Active, N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells. For use in Kinase Assays.,
Species
human
14-748-M
Src (T341M) Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.,
Species
human
14-326-M
Src Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays.,
Species
human

esiRNA

Product Number
Description
Species
EMU071351
MISSION® esiRNA, targeting mouse Src,
Species
mouse

Small Molecule - Substrate

Product Number
Description
Species
12-140
Src Substrate Peptide, Src Substrate Peptide primarily used in Kinase Assays.,
Species
human