S4311
L-Serine
98.5-101.0%, suitable for cell culture, non-animal source, meets EP, USP testing specifications
동의어(들):
L Serine, (S)-2-Amino-3-hydroxypropionic acid
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
HOCH2CH(NH2)CO2H
CAS 번호:
Molecular Weight:
105.09
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-274-3
MDL number:
Beilstein/REAXYS Number:
1721404
제품 이름
L-Serine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%
InChI key
MTCFGRXMJLQNBG-REOHCLBHSA-N
InChI
1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
SMILES string
N[C@@H](CO)C(O)=O
biological source
non-animal source
agency
USP/NF
meets EP testing specifications
meets USP testing specifications
assay
98.5-101.0%
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white
mp
222 °C (dec.) (lit.)
solubility
H2O: 50 mg/mL
application(s)
pharmaceutical (small molecule)
Quality Level
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Application
L-Serine has been used as a supplement in a medium to culture Chinese hamster ovary TF 70R cell line and in mouse embryonic fibroblast (MEF)-media.
Biochem/physiol Actions
L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system.
Precursor of glycine by serine hydroxymethyltransferase.
저장 등급
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Simultaneous environmental manipulations in semi-perfusion cultures of CHO cells producing rh-tPA
Biotechnology (2012)
Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria
Taru Hilander
Nucleic Acids Research (2018)
Abel Lajtha, Simo S. Oja, Pirjo Saransaari, Arne Schousboe
Handbook of Neurochemistry and Molecular Neurobiology: Amino Acids and Peptides in the Nervous System (2007)
Yurena Vivas-García et al.
Molecular cell, 77(1), 120-137 (2019-11-18)
Phenotypic and metabolic heterogeneity within tumors is a major barrier to effective cancer therapy. How metabolism is implicated in specific phenotypes and whether lineage-restricted mechanisms control key metabolic vulnerabilities remain poorly understood. In melanoma, downregulation of the lineage addiction oncogene
Kenji Hashimoto et al.
Progress in neuro-psychopharmacology & biological psychiatry, 29(5), 767-769 (2005-06-09)
Several lines of evidence suggest that D-serine, an endogenous agonist of the glycine site on the NMDA receptors, might play a role in the pathophysiology of schizophrenia. The purpose of this study was to determine whether levels of D- and
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