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S4311

Sigma-Aldrich

L-Serine

from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

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Synonym(s):
L Serine, (S)-2-Amino-3-hydroxypropionic acid
Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
105.09
Beilstein:
1721404
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

biological source

non-animal source

Quality Level

Agency

USP/NF
meets EP testing specifications
meets USP testing specifications

Assay

98.5-101.0%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

222 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

application(s)

pharmaceutical (small molecule)

SMILES string

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI key

MTCFGRXMJLQNBG-REOHCLBHSA-N

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1 of 4

This Item
84959PHR11035650
L-Serine from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

S4311

L-Serine

-
L-Serine BioUltra, ≥99.5% (NT)

Sigma-Aldrich

84959

L-Serine

Premium Grade
L-Serine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1103

L-Serine

-
Millipore

Millipore

5650

L-Serine

-
form

powder

form

powder or crystals

form

-

form

solid

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

impurities

endotoxin, tested

impurities

insoluble matter, passes filter test, ≤0.3% foreign amino acids

impurities

-

impurities

-

color

white

color

white

color

-

color

white

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

mp

-

Application

L-Serine has been used as a supplement in a medium to culture Chinese hamster ovary TF 70R cell line and in mouse embryonic fibroblast (MEF)-media.

Biochem/physiol Actions

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system.
Precursor of glycine by serine hydroxymethyltransferase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria
Taru Hilander
Nucleic Acids Research (2018)
Simultaneous environmental manipulations in semi-perfusion cultures of CHO cells producing rh-tPA
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