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A4159

Sigma-Aldrich

L-Asparagine

BioReagent, suitable for cell culture, suitable for insect cell culture

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Synonym(s):
(S)-2-Aminosuccinic acid 4-amide, L-Aspartic acid 4-amide
Linear Formula:
H2NCOCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
132.12
Beilstein:
1723527
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.75

product line

BioReagent

Quality Level

Assay

≥98% (HPLC)

form

powder

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

color

white

mp

235 °C (dec.) (lit.)

application(s)

agriculture

SMILES string

N[C@@H](CC(N)=O)C(O)=O

InChI

1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1

InChI key

DCXYFEDJOCDNAF-REOHCLBHSA-N

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1 of 4

This Item
A4284A7094A0884
L-Asparagine BioReagent, suitable for cell culture, suitable for insect cell culture

Sigma-Aldrich

A4159

L-Asparagine

-
L-Asparagine monohydrate BioReagent, suitable for cell culture

Sigma-Aldrich

A4284

L-Asparagine monohydrate

-
L-Asparagine monohydrate from non-animal source, BioReagent, suitable for cell culture, ≥98.0%

Sigma-Aldrich

A7094

L-Asparagine monohydrate

Essential+ Grade
L-Asparagine ≥98% (HPLC)

Sigma-Aldrich

A0884

L-Asparagine

-
assay

≥98% (HPLC)

assay

≥99% (TLC)

assay

≥98.0%

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

color

white

color

white to off-white

color

white

color

white

mp

235 °C (dec.) (lit.)

mp

233-235 °C (lit.)

mp

233-235 °C (lit.)

mp

235 °C (dec.) (lit.)

Application

L-Asparagine is used in cell culture media and is a component of MEM non-essential amino acids solution. L-Asparagine has been shown to enhance ornithine decarboxylase activity in cultured human colon adenocarcinoma Caco-2 cells and in cultured IEC-6 intestinal epithelial cells. Spore germination in Bacillus subtilis has been increased in the presence of L-asparagine.
An isoxazoline RGD mimic platelet GPIIb/IIIa antagonist has been prepared by chiral synthesis with L-asparagine as a starting material. L-Asparagine has been utilized in the synthesis of 4-azalysine building blocks for application to combinatorial chemistry.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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705578-5MG-PW

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MMYOMAG-74K-13

1000309185

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Homochiral 4-azalysine building blocks: syntheses and applications in solid-phase chemistry
Chhabra, S. R., et al.
The Journal of Organic Chemistry, 67, 4017-4029 (2002)
The enantiospecific synthesis of an isoxazoline. A RGD mimic platelet GPIIb/IIIa antagonist.
Zhang L. H., et al.
The Journal of Organic Chemistry, 62, 2466-270 (1997)
Interaction of asparagine and EGF in the regulation of ornithine decarboxylase in IEC-6 cells
Ray, R. M., et al.
The American Journal of Physiology, 276 (3 Pt 1), G773-G780 null
Increased translation efficiency and antizyme-dependent stabilization of ornithine decarboxylase in amino acidsupplemented human colon adenocarcinoma cells, Caco-2.
Chabanon, H., et al.
The Biochemical Journal, 348 (Pt 2), 401-408 (2000)
Effects of overexpression of nutrient receptors on germination of spores of Bacillus subtilis
Cabrera-Martinez, R. M., et al.
Journal of Bacteriology, 185, 2457-264 (2003)

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