D1260

Decamethonium bromide

crystalline

• Synonym(s): Decamethylene bis(trimethylammonium bromide), Decane-1,10-bis(trimethylammonium bromide)
• Linear Formula: (CH₃)₃N(Br)(CH₂)₁₀N(Br)(CH₃)₃
• CAS Number: 541-22-0
• Molecular Weight: 418.29
• Beilstein: 3728288
• EC Number: 208-772-2
• MDL number: MFCD00011779
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277833
• NACRES: NA.77

Properties

• form: crystalline
• Quality Level: 200
• color: off-white
• mp: 263-267 °C (lit.)
• originator: GlaxoSmithKline
• SMILES string: [Br-].[Br-].C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C
• InChI: 1S/C16H38N2.2BrH/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2
• InChI key: HLXQFVXURMXRPU-UHFFFAOYSA-L
• Gene Information: human ... CHRNA1(1134) , CHRNA10(57053) , CHRNA2(1135) , CHRNA3(1136) , CHRNA4(1137) , CHRNA5(1138) , CHRNA6(8973) , CHRNA7(1139) , CHRNA9(55584) , CHRNB1(1140) , CHRNB2(1141) , CHRNB3(1142) , CHRNB4(1143) , CHRND(1144) , CHRNE(1145) , CHRNG(1146)

Description

Application

Decamethonium bromide has been used to induce paralysis in duck embryo.

Biochem/physiol Actions

Decamethonium serves as a muscle relaxant and is also a neuromuscular blocking agent. It has a molecular weight of 258.4.

Nicotinic acetylcholine receptor partial agonist and neuromuscular blocking agent; depolarizes striated muscles and blocks their activity.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301,H315,H319,H335
• Precautionary Statements: P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves