D126608

2,6-Diisopropylphenol

97%

• Synonyma: 2,6-Bis(1-methylethyl)phenol, 2,6-Bis(isopropyl)phenol, Propofol
• Lineární vzorec: [(CH₃)₂CH]₂C₆H₃OH
• Číslo CAS: 2078-54-8
• Molekulová hmotnost: 178.27
• NACRES: NA.22
• PubChem Substance ID: 24278001
• UNSPSC Code: 12352100
• EC Number: 218-206-6
• MDL number: MFCD00008885
• Assay: 97%
• Form: liquid

Vlastnosti

• vapor pressure: 5.6 mmHg ( 100 °C)
• Quality Segment: 100
• assay: 97%
• form: liquid
• refractive index: n20/D 1.514 (lit.)
• bp: 256 °C/764 mmHg (lit.)
• mp: 18 °C (lit.)
• density: 0.962 g/mL at 25 °C (lit.)
• SMILES string: CC(C)c1cccc(C(C)C)c1O
• InChI: 1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
• InChI key: OLBCVFGFOZPWHH-UHFFFAOYSA-N
• Gene Information: human ... CYP1A2(1544), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879) ; rat ... Gabra2(29706)

Popis

General description

2,6-Diisopropylphenol, a strongly hydrophobic substituted phenol, is a new intravenous anaesthetic. The antioxidant properties of 2,6-diisopropylphenol (Propofol) have been examined. It plays the role of an antioxidant by reacting with free radicals to form a phenoxyl radical, a property associated with all phenol-based free radical scavengers. 2,6-diisopropylphenol is an effective intravenous hypnotic agent, widely used for the induction and maintenance of anesthesia and for sedation in the intensive care unit. It is useful for the induction and maintenance of general anaesthesia.

Application

2,6-Diisopropylphenol is suitable reagent used to study its effect on oxidative phosphorylation of isolated rat liver mitochondria. It is suitable reagent used in the preparation of bis(2,6-diisopropylphenoxy)bis(2-methyl-8-quinolinolato)titanium(IV) complex.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Skladovací třída: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter