14-304
MKK6/SKK3 Protein, inactive, 50 g
Unactive, recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag, for use in Kinase Assays.
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32
biological source
human
Quality Level
recombinant
expressed in E. coli
mol wt
Mw 80.6 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... MAP2K6(5608)
General description
Product Source: expressed in E. coli
Recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag
Biochem/physiol Actions
Protein Target: MKK6
Target Sub-Family: STE
Quality
routinely evaluated by phosphorylation of MBP
Physical form
affinity chromatography on amylose resin beads
Storage and Stability
6 months at -70C
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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A Dominic Fortes
Acta crystallographica. Section E, Crystallographic communications, 71(Pt 7), 799-806 (2015-08-19)
Time-of-flight neutron powder diffraction data have been measured from ∼90 mol% deuterated isotopologues of Na2MoO4·2H2O and Na2WO4·2H2O at 295 K to a resolution of sin (θ)/λ = 0.77 Å(-1). The use of neutrons has allowed refinement of structural parameters with a precision that varies
A Dominic Fortes
Acta crystallographica. Section E, Crystallographic communications, 71(Pt 6), 592-596 (2015-06-20)
Time-of-flight neutron powder diffraction data have been collected from Na2MoO4 and Na2WO4 to a resolution of sin (θ)/λ = 1.25 Å(-1), which is substanti-ally better than the previous analyses using Mo Kα X-rays, providing roughly triple the number of measured reflections with
Tianxiao Gao et al.
Proceedings of the National Academy of Sciences of the United States of America, 119(4) (2022-01-26)
Proinflammatory cytokine production by innate immune cells plays a crucial role in inflammatory diseases, but the molecular mechanisms controlling the inflammatory responses are poorly understood. Here, we show that TANK-binding kinase 1 (TBK1) serves as a vital regulator of proinflammatory
R Meier et al.
European journal of biochemistry, 236(3), 796-805 (1996-03-15)
The identities of the upstream activators of the mitogen-activated protein (MAP) kinase homologues termed stress-activated-protein (SAP) kinase-1 (also known as JNK or SAPK) and SAP kinase-2 (also known as p38, RK and CSBP) were investigated in rat PC12 cells and
Romina Bertinat et al.
Journal of cellular physiology, 232(2), 355-362 (2016-10-31)
Diabetic kidney disease (DKD) is the major cause of end stage renal disease. Sodium tungstate (NaW) exerts anti-diabetic and immunomodulatory activities in diabetic animal models. Here, we used primary cultures of renal proximal tubule epithelial cells derived from type-2-diabetic (D-RPTEC)
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