MAP2K6
mitogen-activated protein kinase kinase 6
Synonyms:
MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
Species:
Human MAP2K6 (5608), Mouse Map2k6 (26399), Rat Map2k6 (114495), dog MAP2K6 (480454), chicken MAP2K6 (417445), Zebrafish map2k6 (65239), domestic guinea pig Map2k6 (100731419), naked mole-rat Map2k6 (101703028), sheep MAP2K6 (101115047), Domestic Rabbit MAP2K6 (100355230) ...More
UniProtKB ID:
Gene ID:
- Human(5608) Summary: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]
- Mouse(26399) mitogen-activated protein kinase kinase 6
- Rat(114495) mitogen-activated protein kinase kinase 6
- dog(480454) mitogen-activated protein kinase kinase 6
- chicken(417445) mitogen-activated protein kinase kinase 6
- Zebrafish(65239) mitogen-activated protein kinase kinase 6
- domestic guinea pig(100731419) mitogen-activated protein kinase kinase 6
- naked mole-rat(101703028) mitogen-activated protein kinase kinase 6
- sheep(101115047) mitogen-activated protein kinase kinase 6
- Domestic Rabbit(100355230) mitogen-activated protein kinase kinase 6
- cow(286883) mitogen-activated protein kinase kinase 6
- domestic cat(101089813) mitogen-activated protein kinase kinase 6
- Horse(100053056) mitogen-activated protein kinase kinase 6
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MKK6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MAP2K6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-MAP2K6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-MAP2K6 antibody produced in mouse, clone 2F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
MKK6 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE),
Species
human
MKK6/SKK3, active human, ≥80% (SDS-PAGE), recombinant, expressed in E. coli, Maltose binding protein tagged, buffered aqueous solution,
Species
human
MKK6/SKK3 Protein, inactive, 50 g, Unactive, recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag, for use in Kinase Assays.,
Species
human
MKK6/SKK3 (S599D, T603D) Protein, active, 10 µg, Active, N-terminal MBP tagged, recombinant, human MKK6/SKK3 residues 4-end containing S599D & T603D mutations. For use in Kinase Assays.,
Species
human
MKK6/SKK3 Protein, active, 10 µg, Active, N-terminal, maltose binding protein tagged, human MKK6/SKK3 fusion protein, amino acids 4-end. For use in Kinase Assays.,
Species
human