19533
Geranyl pyrophosphate lithium salt
analytical standard
Synonym(s):
(E)-3,7-Dimethyl-2,6-octadien-1-ol trihydrogen pyrophosphate lithium salt, (E)-3,7-Dimethyl-2,6-octadien-1-yl pyrophosphate lithium salt, GPP-Li
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About This Item
Empirical Formula (Hill Notation):
C10H20O7P2 · xLi+
CAS Number:
Molecular Weight:
314.21 (free acid basis)
Beilstein:
1915690
UNSPSC Code:
85151701
NACRES:
NA.24
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Quality Level
grade
analytical standard
Assay
≥95.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
shipped in
dry ice
storage temp.
−20°C
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Analysis Note
NMR-Internal Standard : KHP
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Akira Saito et al.
Melanoma research, 18(2), 85-94 (2008-03-14)
Competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (the statins) that inhibit the synthesis of mevalonic acid are in wide use for treatment of hypercholesterolemia. Although antitumor effects on a variety of cell types have been reported for statins, the effect
Joris W De Schutter et al.
Bioorganic & medicinal chemistry letters, 20(19), 5781-5786 (2010-08-31)
A structure-based approach was pursued in designing novel bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase (hFPPS). Preliminary SAR and structural evidence for the simultaneous binding of these inhibitors into the isopentenyl pyrophosphate (IPP) and the geranyl pyrophosphate (GPP) substrate
J Fraser Glickman et al.
Assay and drug development technologies, 5(2), 205-214 (2007-05-05)
A mix-and-read FlashPlate (PerkinElmer, Waltham, MA) assay for the enzyme farnesyl pyrophosphate (FPP) synthase (FPPS) was developed to rapidly measure both steps in the synthesis of FPP from dimethylallyl pyrophosphate (DMAPP). The assay used either DMAPP or geranyl pyrophosphate (GPP)
Ken'ichi Hagiwara et al.
Biochemistry, 43(2), 300-309 (2004-01-14)
Farnesylation of the gamma-subunit of the retinal G-protein, transducin (Talpha/Tbetagamma), is indispensable for light-initiated signaling in photoreceptor cells. However, the farnesyl-mediated molecular interactions important for signaling are not well understood. To explore this issue, we created a functional Tbetagamma analogue
Kuan-Hung Chen et al.
The Journal of organic chemistry, 74(2), 895-898 (2008-12-04)
Hexaamide receptor 4 and coumarin phosphate 5 form an ensemble for effective sensing of geranyl pyrophosphate (GPP). Fluorescence resonance energy transfer in the 4 + 5 ensemble diminishes when 5 is replaced by GPP. Receptor 4 binds selectively with GPP
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