Skip to Content
Merck
All Photos(2)

Documents

1.01040

Supelco

2-Propanol

≥99.9% (GC), gradient grade, suitable for HPLC, LiChrosolv®

Synonym(s):

sec-Propyl alcohol, IPA, Isopropanol, Isopropyl alcohol

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
(CH3)2CHOH
CAS Number:
Molecular Weight:
60.10
Beilstein:
635639
MDL number:
UNSPSC Code:
12191502
EC Index Number:
200-661-7
NACRES:
NA.03

product name

2-Propanol, gradient grade for liquid chromatography LiChrosolv®

vapor density

2.1 (vs air)

Quality Level

vapor pressure

33 mmHg ( 20 °C)
43 hPa ( 20 °C)
44 mmHg ( 25 °C)

product line

LiChrosolv®

grade

gradient grade

Assay

≥99.9% (GC)

form

liquid

autoignition temp.

750 °F

potency

5045 mg/kg LD50, oral (Rat)
12800 mg/kg LD50, skin (Rabbit)

expl. lim.

2.0-12.7 %, 93 °C

technique(s)

HPLC: suitable

impurities

≤0.0002 meq/g Acidity
≤0.0002 meq/g Alkalinity
≤0.05% Water

evapn. residue

≤2.0 mg/L

transmittance

220 nm, ≥80% (Checking after purging with N2)
230 nm, ≥90% (Checking after purging with N2)
250 nm, ≥99% (Checking after purging with N2)

refractive index

n20/D 1.377 (lit.)

pH

7 (20 °C)

bp

82 °C (lit.)

mp

−89.5 °C (lit.)

transition temp

flash point 12 °C

density

0.785 g/mL at 25 °C (lit.)

storage temp.

2-25°C

SMILES string

CC(C)O

InChI

1S/C3H8O/c1-3(2)4/h3-4H,1-2H3

InChI key

KFZMGEQAYNKOFK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

With their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in "gradient grade" as well as "isocratic grade". This enables to minimize the gradient effect of the solvent involved.

Application

2-Propanol is used as a solvent to:
  • prepare the isocratic mobile phase for reversed phase LC-MS-MS analysis.
  • prepare stock solution of the phospholipid species.
  • wash the slide during hematoxylin and eosin (H&E) staining procedure.

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Purity (GC): ≥ 99.9 %
Identity (IR): conforms
Evaporation residue: ≤ 2.0 mg/l
Water: ≤ 0.05 %
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Gradient grade (at 235 nm): ≤ 1.0 mAU
Gradient grade (at 254 nm): ≤ 1.0 mAU
Transmission (Checking after purging with N₂ (at 220 nm)): ≥ 80 %
Transmission (Checking after purging with N₂ (at 230 nm)): ≥ 90 %
Transmission (Checking after purging with N₂ (from 250 nm)): ≥ 99 %
  Filtered by 0.2 µm filter

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

53.6 °F - closed cup

Flash Point(C)

12.0 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

N-Glycan matrix-assisted laser desorption/ionization mass spectrometry imaging protocol for formalin-fixed paraffin-embedded tissues.
Matthew B T, et al.
Rapid Communications in Mass Spectrometry, 31, 825-841 (2017)
Temperature optimization for improved determination of phosphatidylserine species by micro liquid chromatography with electrospray tandem mass spectrometric detection.
smund L, et al.
Journal of Separation Science, 27, 297-303 (2004)

Articles

Analyze Xiaoer Chiqiao Qingre granules for geniposide and forsythin using Discovery® HS C18 column and Supelclean™ LC-Alumina-N SPE.

A complete reversed phase HPLC-ELSD workflow, including sample preparation for the analysis of Polysorbate 80 in a monoclonal antibody formulation.

Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

Protocols

Thin layer chromatography coupled with mass spectrometry does not require substantial sample preparation. Energy drinks can be applied without dilution directly onto the TLC plate.

HPTLC–MS analysis of quinine in tonic water and caffeine in coffee and cola drinks.

The modern thin-layer chromatography (TLC) offers advantages also in the field of cosmetics to quickly and simultaneously analyze samples with densitometric detection.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service