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H6508

Sigma-Aldrich

Heparin−Agarose

Type I, saline suspension

Synonym(s):

Heparin beads, Heparin resin

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About This Item

MDL number:
MFCD00163876
UNSPSC Code:
23151817
NACRES:
NA.56

biological source

heparin from Porcine intestinal mucosa

type

Type I

form

saline suspension

extent of labeling

400-1500 μg per mL packed gel (activity approx. 140 USP units per mg)

technique(s)

affinity chromatography: suitable

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

suitability

suitable for chromatography

storage temp.

2-8°C

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Application

Heparin-agarose is developed from porcine intestinal mucosa and is used in affinity chromatography. Heparin-agarose has been used in studies to provide information on human monocytic ehrlichiosis, tumor necrosis and the effects of coagulation from Vipera snake venom.

Physical form

Suspension in 0.5 M NaCl containing preservative

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M E Silvestri et al.
Scandinavian journal of immunology, 53(3), 282-289 (2001-03-17)
An investigation was performed into the heparin-binding properties of a synthetic peptide deduced from the sequence of human cytomegalovirus glycoprotein B. The peptide, T7-13:3, amino acids 69-78, which was previously shown to contain a neutralization epitope was able to bind
91. Universal purification of AAV serotypes 1?5 modified to contain a heparin binding epitope.
Faust, S.M., et al.
Molecular Therapy, 9, S36-S36 (2004)
L C Andersen et al.
The Journal of experimental medicine, 173(1), 181-192 (1991-01-01)
Class II genes of the human major histocompatibility complex (MHC) are highly polymorphic. Allelic variation of structural genes provides diversity in immune cell interactions, contributing to the formation of the T cell repertoire and to susceptibility to certain autoimmune diseases.
G Glaser et al.
Archives of virology, 143(10), 1967-1983 (1998-12-18)
The immediate early BRLF1 and BZLF1 promoters of Epstein-Barr virus are crucial for triggering the replicative cycle of the virus. To better understand the cell type dependence of the lytic cycle we conducted an analysis of the BRLF1-promoter in the
Alejandra Loyola et al.
Methods (San Diego, Calif.), 31(1), 96-103 (2003-08-02)
It is becoming clear that the structure of cellular chromatin is dynamic and capable of undergoing rapid changes to respond to the metabolic requirements of the cell. These changes have a direct impact on gene expression and, therefore, the chromatin
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