Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

309346

Sigma-Aldrich

L-Glutamic acid diethyl ester hydrochloride

97%

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
C2H5OCOCH2CH2CH(NH2)COOC2H5 · HCl
CAS Number:
1118-89-4
Molecular Weight:
239.70
Beilstein:
3597595
EC Number:
214-270-4
MDL number:
MFCD00012509
UNSPSC Code:
12352209
PubChem Substance ID:
24858729
NACRES:
NA.22

Quality Level

200

Assay

97%

optical activity

[α]18/D +22°, c = 1 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

108-110 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cl[H].CCOC(=O)CC[C@H](N)C(=O)OCC

InChI

1S/C9H17NO4.ClH/c1-3-13-8(11)6-5-7(10)9(12)14-4-2;/h7H,3-6,10H2,1-2H3;1H/t7-;/m0./s1

InChI key

WSEQLMQNPBNMSL-FJXQXJEOSA-N

Looking for similar products? Visit Product Comparison Guide

Application

L-Glutamic acid diethyl ester hydrochloride can be used in the synthesis of:
  • Oligo(γ-ethyl L-glutamate) via oligomerization catalyzed by papain.
  • L-glutamic acid based dendritic compounds.
  • Poly(α-peptide) by polymerization and copolymerization in the presence of protease catalysts.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000242152
0000128919
MKCK5271
MKAA3937V
BCBJ4838V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ultrasound induced formation of organogel from a glutamic dendron
Li Y, et al.
Tetrahedron, 63(31), 7468-7473 (2007)
Rapid regioselective oligomerization of L-glutamic acid diethyl ester catalyzed by papain
Li G, et al.
Macromolecules, 39(23), 7915-7921 (2006)
F Barnabi et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 281(5), R1665-R1674 (2001-10-20)
Neurotransmitters relaying ascending visceral information were examined by comparing the response of neurons in the insular cortex to vagal stimulation (0.8 Hz, 2 mA) before and after neurotransmitter antagonist injections (200 nl) in the ventroposterior parvocellular nucleus of the thalamus
B W Peeters et al.
Brain research bulletin, 33(6), 715-718 (1994-01-01)
The interaction between NMDA and nonNMDA receptors was studied in nonconvulsive epilepsy in WAG/Rij rats. Compounds acting on NMDA (NMDA, APH) and nonNMDA (AMPA, GDEE, kainic acid, kynurenic acid) receptors were coinjected intracerebroventricularly. The WAG/Rij rat strain may be an
Asako Narai-Kanayama et al.
Biochimica et biophysica acta, 1780(6), 881-891 (2008-04-15)
Papain polymerizes L-glutamic acid diethyl ester (Glu-di-OEt) regioselectively, resulting in the formation of poly (gamma-ethyl alpha-L-glutamic acid) with various degrees of polymerization of less than 13. Reaction temperatures below 20 degrees C were appropriate for the reaction in terms of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service