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Key Documents

Safety Information

L023050

Sigma-Aldrich

DCA Deblock

configured for ÄKTA® and OligoPilot®, with Toluene

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About This Item

UNSPSC Code:
41116105
NACRES:
NA.21

Quality Level

type

for DNA synthesis
for DNA synthesis

product line

Proligo Reagents

storage condition

dry at room temperature

concentration

42.2-51.6 g/L (DCA content, titration)

impurities

≤200 ppm water content (Karl Fischer)

color

clear

compatibility

configured for ÄKTA® and OligoPilot®

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Preparation Note

Toluene / Dichloroacetic acid 97/3 (v/v)

Other Notes

Deblock solution containing dichloroacetic acid (DCA) in toluene removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.

Legal Information

OligoPilot is a registered trademark of Cytiva
ÄKTA is a registered trademark of Cytiva

Signal Word

Danger

Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Lact. - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

39.2 °F - closed cup

Flash Point(C)

4 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

L023050-200L:
L023050-180L:
L023050-400L:
L023050-4X2.5L:4548173341279
L023050-500ML:
L023050-1400L:
L023050-4X4L:
L023050-2.5L:4548173921419
L023050-45L:
L023050-C:


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