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Safety Information

228710

Sigma-Aldrich

Sodium nitroferricyanide(III) dihydrate

ACS reagent, ≥99%

Synonym(s):

Nitroprusside sodium, SNP, Sodium nitroprusside, Sodium pentacyanonitrosylferrate

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About This Item

Linear Formula:
Na2[Fe(CN)5NO] · 2H2O
CAS Number:
13755-38-9
Molecular Weight:
297.95
EC Number:
238-373-9
MDL number:
MFCD00149192
UNSPSC Code:
12352300
PubChem Substance ID:
329752353
NACRES:
NA.21
Assay:
≥99%
grade:
ACS reagent
form:
crystals

grade

ACS reagent

Quality Level

200

Assay

≥99%

form

crystals

reaction suitability

reagent type: catalyst
core: iron

impurities

≤0.01% insolubles

anion traces

chloride (Cl-): ≤0.02%
sulfate (SO42-): passes test (lim. ~1%)

SMILES string

[Na+].[Na+].[H]O[H].[H]O[H].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N

InChI

1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;;

InChI key

OIRZWVYIQXBRFC-UHFFFAOYSA-N

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General description

Sodium nitroferricyanide(III) dihydrate (sodium nitroprusside dihydrate, SNP) is a dihydrate form of sodium nitroprusside. It is comprised of ferrous iron complexed with nitric oxide (NO) and five cyanide ions. It serves as a donor of nitric oxide.

Application

Sodium nitroferricyanide(III) dihydrate can be used as a reagent to produce nitric oxide radicals (NO) via UV radiation-induced photolysis. These radicals are employed for the construction of amino acid-based supramolecular hydrogels, which find potential applications in disease diagnosis and therapy including bioimaging, bio-detection, therapeutic delivery, and tissue engineering. Additionally, SNP also serves as a catalyst in the Phenate Method for the quantitative measurement of ammonia in water samples.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Poisonous substance

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

228710-100G:4548173120164
228710-BULK:
228710-VAR:
228710-500G:4548173120171
228710-5G:4548173120188

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW6439
MKCV8286
MKCT2965
MKCT2708
MKCV4346

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Polyhedron, 22, 2527-2535 (2003)
Anal. Profiles Drug Subst., 6, 487-513 (1977)
Oluwatobiloba Osikoya et al.
The Journal of physiology, 597(15), 3833-3852 (2019-06-06)
In vivo, uterine perivascular adipose tissue (PVAT) potentiates uterine artery blood flow in pregnant rats, although not in non-pregnant rats. In isolated preparations, uterine PVAT has pro-contractile and anti-dilatory effects on uterine arteries. Pregnancy induces changes in uterine arteries that
Milos R Filipovic et al.
Journal of medicinal chemistry, 56(4), 1499-1508 (2013-02-20)
Hydrogen sulfide (H2S) has been increasingly recognized as an important signaling molecule that regulates both blood pressure and neuronal activity. Attention has been drawn to its interactions with another gasotransmitter, nitric oxide (NO). Here, we provide evidence that the physiological
Song Guo et al.
Cephalalgia : an international journal of headache, 33(5), 301-307 (2013-02-14)
Sodium nitroprusside (SNP) is a powerful vasodilatory agent that, similarly to glyceryl trinitrate (GTN), releases nitric oxide (NO) but in contrast does not pass the blood-brain barrier. Nevertheless, it has already been used in animal models without any knowledge of
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