Skip to Content
Merck
All Photos(1)

Key Documents

534587

Sigma-Aldrich

(S)-(+)-2-Amino-1-pentanol

97%

Synonym(s):

L-Norvalinol

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3(CH2)2CH(NH2)CH2OH
CAS Number:
Molecular Weight:
103.16
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

optical activity

[α]20/D +17°, c = 1 in chloroform

mp

44-48 °C (lit.)

SMILES string

CCC[C@H](N)CO

InChI

1S/C5H13NO/c1-2-3-5(6)4-7/h5,7H,2-4,6H2,1H3/t5-/m0/s1

InChI key

ULAXUFGARZZKTK-YFKPBYRVSA-N

Application

(S)-(+)-2-Amino-1-pentanol can be used:
  • As a model compound in the study of estimation of dilution enthalpies of (R)-(−)-2-amino-1-pentanol in DMSO+H2O mixtures using isothermal titration calorimeter.
  • As a substrate to prepare tricyclic heterocyclic compounds as possible antagonists of corticotropin-releasing factor-1.
  • As an intermediate in one of the key synthetic steps for the preparation of an antiviral agent telaprevir.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

213.8 °F - closed cup

Flash Point(C)

101 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ugi and Passerini reactions of biocatalytically derived chiral aldehydes: application to the synthesis of bicyclic pyrrolidines and of antiviral agent telaprevir
Moni L, et al.
The Journal of Organic Chemistry, 80(7), 3411-3428 (2015)
Pairwise interaction enthalpies of enantiomers of β-amino alcohols in DMSO+ H2O mixtures at 298.15 K
Liang H, et al.
Chirality, 24(5), 374-385 (2012)
Design and synthesis of tricyclic corticotropin-releasing factor-1 antagonists
Gross RS, et al.
Journal of Medicinal Chemistry, 48(18), 5780-5793 (2005)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service