추천 제품
설명
cholest-5-ene-3β,24(R)-diol
분석
>99% (TLC)
형태
powder
포장
pkg of 1 × 1 mg (700071P-1mg)
제조업체/상표
Avanti Research™ - A Croda Brand
배송 상태
dry ice
저장 온도
−20°C
일반 설명
24-hydroxycholesterol (24-OH) is an oxidized product of cholesterol. It is synthesized in the presence of enzyme 24S-hydroxylase (CYP46A1).
생화학적/생리학적 작용
24(S)-hydroxycholesterol is preferred over 24(R)-hydroxycholesterol by human 7α-hydroxylase. However, the porcine enzyme is active towards both isomers. 24-hydroxycholesterol (24-OH) favors sirtuin 1 expression and reduces the tau protein phosphorylation.
포장
5 mL Amber Glass Screw Cap Vial (700071P-1mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
No data available
Flash Point (°C)
No data available
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
M Norlin et al.
Journal of lipid research, 41(10), 1629-1639 (2000-10-03)
(24S)-Hydroxycholesterol is formed from cholesterol in the brain and is important for cholesterol homeostasis in this organ. Elimination of (24S)-hydroxycholesterol has been suggested to occur in the liver but little is known about the metabolism of this oxysterol. In the
Gabriella Testa et al.
Redox biology, 17, 423-431 (2018-06-09)
It is now established that cholesterol oxidation products (oxysterols) are involved in several events underlying Alzheimer's disease (AD) pathogenesis. Of note, certain oxysterols cause neuron dysfunction and degeneration but, recently, some of them have been shown also to have neuroprotective
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.