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Merck
모든 사진(1)

문서

MAB1578

Sigma-Aldrich

Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2

clone 18C7.2, Chemicon®, from mouse

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified antibody

항체 생산 유형

primary antibodies

클론

18C7.2, monoclonal

정제법

using Protein A

종 반응성

monkey

제조업체/상표

Chemicon®

기술

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

동형

IgG1

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

rhesus monkey ... Chrm4(574195)

특이성

m4 muscarinic acetylcholine receptor. No reactivity with the other subtypes.

면역원

m4 receptor i3 loop (human), fused to GST

애플리케이션

Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2 detects level of Muscarinic Acetylcholine Receptor m4 & has been published & validated for use in IH, IP & WB.
Immunohistochemistry (monkey)

Western blot (transfected CHO cell lines)

Immunoprecipitation (rat and monkey)

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

물리적 형태

Liquid in 0.02M Phosphate buffer, 0.25 M NaCl with 0.1% sodium azide.

저장 및 안정성

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Deborah Bauer et al.
Schizophrenia research, 117(1), 92-98 (2009-09-01)
The excitatory amino acid transporters (EAATs) are a family of molecules that are essential for regulation of synaptic glutamate levels. The EAATs may also be regulated by N-glycosylation, a posttranslational modification that is critical for many cellular functions including localization
G Q Li et al.
Neuroscience, 146(1), 384-402 (2007-03-30)
Muscarinic acetylcholine receptors (mAChRs) are widely expressed in the CNS and peripheral nervous system and play an important role in modulating the cell activity and function. We have shown that the cholinergic agonist carbachol reduces the pigeon's inwardly rectifying potassium
Christianne E Strang et al.
Investigative ophthalmology & visual science, 51(5), 2778-2789 (2010-01-01)
The activation and blockade of muscarinic acetylcholine receptors (mAChRs) affects retinal ganglion cell light responses and firing rates. This study was undertaken to identify the full complement of mAChRs expressed in the rabbit retina and to assess mAChR distribution and
Judith Molina et al.
Diabetes, 63(8), 2714-2726 (2014-03-25)
Acetylcholine regulates hormone secretion from the pancreatic islet and is thus crucial for glucose homeostasis. Little is known, however, about acetylcholine (cholinergic) signaling in the human islet. We recently reported that in the human islet, acetylcholine is primarily a paracrine
Jivan Khlghatyan et al.
Cerebral cortex (New York, N.Y. : 1991), 29(9), 3813-3827 (2018-10-09)
Cortical D2 dopamine receptor (Drd2) have mostly been examined in the context of cognitive function regulation and neurotransmission modulation of medial prefrontal cortex by principal neurons and parvalbumin positive, fast-spiking, interneurons in schizophrenia. Early studies suggested the presence of D2

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