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Merck
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주요 문서

ROAMYGL

Roche

Amyloglucosidase

from Aspergillus niger

동의어(들):

Glucoamylase, disaccharidase-type-α-D-glucosidase

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About This Item

효소 위원회 번호:
UNSPSC 코드:
12352204

생물학적 소스

Aspergillus niger

Quality Level

양식

suspension

특이 활성도

~14 units/mg protein (At 25 °C with glycogen as the substrate; standardized with BSA.)

분자량

Mr 97 kDa

포장

pkg of 10 mL (10102857001 [100 mg])

제조업체/상표

Roche

파라미터

55 °C optimum reaction temp.

최적 pH

4.6-4.8

저장 온도

2-8°C

관련 카테고리

일반 설명

Amyloglucosidase is synthesized by several Aspergillus genus species. It is a disaccharidase–type α-glucosidase. This enzyme is an exo-enzyme and one of the major industrial enzymes. The stability of amyloglucosidase can be increased by immobilization.

특이성

Cleaves terminal glucoses that are α1,4- or α1,6-linked to an oligo- or polysaccharide of multiple glucose units. The product is D-glucose.
Heat inactivation: Heat inactivation is recommended at 80 °C for 45 minutes, followed by rapidly cooling down.

애플리케이션

Amyloglucosidase from Aspergillus niger can be used for the hydrolyzation of terminal α1,4- and α1,6-glucosidic bonds (glucose-glucose bonds) in polysaccharides (e.g., starch, dextrins, glycogen), removing glucose units sequentially from the non-reducing end of the molecule. The enzyme will also cleave maltose and maltosides (maltotriose, maltotetraose, etc.).

생화학적/생리학적 작용

Amyloglucosidase from Aspergillus niger is capable of hydrolyzing the α-D-(1-4), the α-D-(1-6), and the α-D-(1-3) glucosidic bonds of oligosaccharides. Amyloglucosidase is an extracellular enzyme that converts starch to dextrins and glucose. The enzyme is used in the starch-processing industry for the commercial production of D-glucose from corn syrups.

단위 정의

Unit Conversion: One unit (+25 °C; glycogen as substrate) corresponds to 8.6 U (+60 °C; starch as substrate).

물리적 형태

Suspension in 3.2 M ammonium sulfate solution, pH approximately 6

기타 정보

For life science research only. Not for use in diagnostic procedures.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

does not flash

Flash Point (°C)

does not flash


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문서 라이브러리 방문

High-potency amyloglucosidase-producing mold of the Aspergillus niger group.
Smiley KL, et al.
Applied Microbiology, 12(5), 455-455 (1964)
A A Amirul et al.
Folia microbiologica, 41(2), 165-174 (1996-01-01)
A. niger produced alpha-glucosidase, alpha-amylase and two forms of glucoamylase when grown in a liquid medium containing raw tapioca starch as the carbon source. The glucoamylases, which formed the dominant components of amylolytic activity manifested by the organism, were purified
Recent Advances in Basic and Applied Aspects of Industrial Catalysis (1998)
Guang W Wong et al.
Proceedings of the National Academy of Sciences of the United States of America, 101(28), 10302-10307 (2004-07-03)
Biochemical, genetic, and animal studies in recent years have established a critical role for the adipokine Acrp30/adiponectin in controlling whole-body metabolism, particularly by enhancing insulin sensitivity in muscle and liver, and by increasing fatty acid oxidation in muscle. We describe
TOR acts as a metabolic gatekeeper for auxin-dependent lateral root initiation in Arabidopsis thaliana.
Stitz, et al.
The Embo Journal, 42, e111273-e111273 (2023)

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