A9519

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate

≥98% (TLC), suitable for ligand binding assays

• 동의어(들): Adjuvant Peptide, Muramyl dipeptide
• 실험식(Hill 표기법): C₁₉H₃₂N₄O₁₁ · xH₂O
• CAS Number: 53678-77-6
• Molecular Weight: 492.48 (anhydrous basis)
• Beilstein: 4220745
• EC Number: 258-696-9
• MDL number: MFCD00077638
• UNSPSC 코드: 12352209
• PubChem Substance ID: 24891464
• NACRES: NA.26

속성

• product name: N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate, ≥98% (TLC)
• 분석: ≥98% (TLC)
• 형태: powder
• 기술: ligand binding assay: suitable
• 색상: white
• 응용 분야: cell analysis
• 저장 온도: −20°C
• SMILES string: C[C@H](NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1NC(C)=O)C(=O)N[C@H](CCC(O)=O)C(N)=O
• InChI: 1S/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11+,13+,14+,15+,19?/m0/s1
• InChI key: BSOQXXWZTUDTEL-QAQREVAFSA-N

설명

Amino Acid Sequence

MurNAc-Ala-Agn

애플리케이션

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate has been used in staphylococcal cell wall preparation to induce the release of TNF from human monocytes.

생화학적/생리학적 작용

Enhances antigenicity of weak antigens, increasing antibody titer.

Muramyl peptides are monomeric components that make up the bacterial cell wall peptidoglycan. It is generally produced by mammalian macrophages, as an immune response in the breakdown of bacterial cell wall. MDP promotes the production of interleukin-1 and tumor necrosis factor (TNF), which increase slow-wave sleep.

N-Acetylmuramyl-L-alanyl-D-isoglutamine (MDP, muramyl dipeptide), a neurotrophic and immunomodulatory factor related to bacterial peptidoglycans, is used as an immune modulation factor that enhances immune response and to study neural development.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)