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Merck
모든 사진(1)

주요 문서

D2779

Sigma-Aldrich

Dimethyldioctadecylammonium bromide

≥98% (TLC)

동의어(들):

Distearyldimethylammonium bromide

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About This Item

Linear Formula:
[CH3(CH2)17]2N(Br)(CH3)2
CAS Number:
Molecular Weight:
630.95
Beilstein:
3580323
EC Number:
MDL number:
UNSPSC 코드:
12161900
PubChem Substance ID:
NACRES:
NA.25

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설명

cationic

분석

≥98% (TLC)

양식

powder

분자량

630.95 g/mol

mp

~160 °C

응용 분야

cell analysis

SMILES string

CCCCCCCCCCCCCCCCCC[N+](CCCCCCCCCCCCCCCCCC)(C)C.[Br-]

InChI

1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1

InChI key

PSLWZOIUBRXAQW-UHFFFAOYSA-M

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일반 설명

Dimethyldioctadecylammonium bromide is a cationic lipid that stimulates immune responses, activates macrophages, and binds to antigens. [1]

애플리케이션

Dimethyldioctadecylammonium bromide has been used in a study to assess the interaction of its monolayers with DNA using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. [2] It has also been used in a study to investigate new adjuvants for use in kill vaccines for bovine viral diarrhea virus (BVDV). [3]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

F S Baechtel et al.
Cancer research, 42(12), 4959-4963 (1982-12-01)
Dimethyldioctadecylammonium bromide (DDA) stimulates immune responses, primes (or activates) macrophages, and binds to antigens. Because relatively little is known about the binding of adjuvants to antigens, the nature of the interaction of DDA with soluble protein and cellular antigens was
Julia F Ridpath et al.
Veterinary research communications, 34(8), 691-702 (2010-09-28)
Bovine viral diarrhea virus (BVDV) infections cause respiratory, reproductive, and enteric disease in cattle. Vaccination raises herd resistance and limits the spread of BVDV among cattle. Both killed and modified live vaccines against BVDV are available. While modified live vaccines
Randip Kaur et al.
Journal of controlled release : official journal of the Controlled Release Society, 158(1), 72-77 (2011-10-29)
The adjuvant efficacy of cationic liposomes composed of dimethyldioctadecylammonium bromide and trehalose dibehenate (DDA:TDB) is well established. Whilst the mechanism behind its immunostimulatory action is not fully understood, the ability of the formulation to promote a 'depot effect' is a
Julio H K Rozenfeld et al.
Journal of controlled release : official journal of the Controlled Release Society, 160(2), 367-373 (2011-11-01)
The cationic lipid dioctadecyldimethylammonium bromide (DODAB) and the CpG oligonucleotide (CpG) have been separately used as potent immunoadjuvants driving Th1 responses. Here DODAB bilayer fragments (BF) and CpG (5'-TTGACGTTCG-3') assemblies have their physical properties and immunoadjuvant activity determined using ovalbumin
Deepesh Bhardwaj et al.
Journal of hazardous materials, 227-228, 292-300 (2012-06-12)
This article introduces the synthesis of clinoptilolite and montmorillonite, and their surfactant modification by using solutions of hexadecyltrimethylammonium bromide (CH(3)(CH(2))(15)N(Br)(CH(3))(3), HDTMAB) and dioctadecyldimethylammonium bromide ((CH(3)(CH(2))(17))(2)N(Br)(CH(3))(2), DODMAB). The feasibility of using surfactant modified silicates (SMSs) as a potential adsorbent for nitrate

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