D6883

2′,7′-Dichlorodihydrofluorescein diacetate

≥97% (HPLC), powder, cell-permeable non-fluorescent probe

• 동의어(들): 2′,7′-Dichlorofluorescin diacetate, DCFH-DA, 2′,7′-Dichlorodihydrofluorescein diacetate
• 실험식(Hill 표기법): C₂₄H₁₆Cl₂O₇
• CAS Number: 4091-99-0
• Molecular Weight: 487.29
• Beilstein: 4610273
• MDL number: MFCD00128955
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24894058
• NACRES: NA.77

속성

• product name: 2′,7′-Dichlorodihydrofluorescein diacetate, ≥97%
• Quality Level: 200
• 분석: ≥97%
• 형태: powder
• 저장 온도: −20°C
• SMILES string: CC(=O)Oc1cc2Oc3cc(OC(C)=O)c(Cl)cc3C(c2cc1Cl)c4ccccc4C(O)=O
• InChI: 1S/C24H16Cl2O7/c1-11(27)31-21-9-19-15(7-17(21)25)23(13-5-3-4-6-14(13)24(29)30)16-8-18(26)22(32-12(2)28)10-20(16)33-19/h3-10,23H,1-2H3,(H,29,30)
• InChI key: PXEZTIWVRVSYOK-UHFFFAOYSA-N

설명

일반 설명

2′,7′-Dichlorodihydrofluorescein diacetate (DCFH-DA) is an oxidation-sensitive fluorescent dye used to detect the intracellular reactive oxygen species (ROS) level. DCFH-DA is a cell-permeable non-fluorescent probe, that can be hydrolyzed by intracellular esterase to DCFH, which forms fluorescent DCF when oxidized by the intracellular ROS.

애플리케이션

2′,7′-Dichlorofluorescin diacetate is suitable for use in:

• sensitive and rapid quantitation of oxygen-reactive species in response to oxidative metabolism
• microplate assay for detecting oxidative products in phagocytic cells
• quantitative multiwell myeloid differentiation assay

Applications include sensitive and rapid quantitation of oxygen-reactive species in response to oxidative metabolism; microplate assay for detecting oxidative products in phagocytic cells, and quantitative multiwell myeloid differentiation assay.

저장 및 안정성

This product should be stored in powdered format at -20°C.

기타 정보

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)