추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
ascites fluid
항체 생산 유형
secondary antibodies
클론
GT-34, monoclonal
포함
15 mM sodium azide
종 반응성
sheep, goat, bovine
반응하면 안 됨
rat, canine, mouse, rabbit, guinea pig, chicken, horse, pig, feline, human
기술
indirect ELISA: 1:10,000-1:20,000
동형
IgG1
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
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일반 설명
IgG is the main type of antibody in human serum, secreted by the B cells. It is found in blood. IgG consists of four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, which are linked by inter-chain disulfide bonds. IgG contains four isotypes IgG1, IgG2, IgG3 and IgG4.
The antibody reacts with an epitope located on the heavy chain of goat IgG1 and IgG2.
특이성
Monoclonal Anti-Goat/Sheep IgG recognizes an epitope located on the heavy chain of goat IgG1 and IgG2. The antibody shows strong cross-reactivity with sheep IgG and weak cross-reactivity with bovine IgG. No cross-reactivity is observed with IgG derived from human, guinea pig, rat, horse, dog, chicken, pig, mouse, rabbit, or cat.
애플리케이션
Monoclonal Anti-Goat/Sheep IgG antibody produced in mouse has been used in:
- enzyme linked immunosorbent assay (ELISA)
- immunoblotting
- immunoprecipitation
- immunoelectrophoresis
생화학적/생리학적 작용
IgG stimulates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC). IgG might be associated with allergy. It has the longest serum half life.
물리적 형태
The product is provided as ascites fluid with 0.1% sodium azide as preservative.
저장 및 안정성
For continuous use, store at 2–8 °C for up to one month. For extended storage, solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify by centrifugation before use.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Tom N McNeilly et al.
Veterinary research, 44, 70-70 (2013-08-24)
Teladorsagia circumcincta is an important pathogenic nematode of sheep. It has been demonstrated previously that stimulation of murine T lymphocytes with excretory-secretory (ES) products derived from fourth stage larvae of T. circumcincta (Tci-L4-ES) results in de novo expression of Foxp3
Seasonal variations of phagocytic response, immunoglobulin G (IgG) and plasma cortisol levels in Dhofari goats
Al-Busaidi R, et al.
Small Ruminant Research, 79(2-3), 118-123 (2008)
Guillaume Sallé et al.
International journal for parasitology, 48(5), 395-402 (2018-03-15)
Some nematode species are economically important parasites of livestock, while others are important human pathogens causing some of the most important neglected tropical diseases. In both humans and animals, anthelmintic drug administration is the main control strategy, but the emergence
Reconstitution of Microtubule Nucleation InA Vitro Reveals Novel Roles for Mzt1.
Leong, et al.
Current Biology, 33, 1864-1864 (2023)
Brett Roberts et al.
Veterinary research, 44(1), 111-111 (2013-12-03)
With the problem of parasitic nematode drug resistance increasing, vaccine development offers an alternative sustainable control approach. For some parasitic nematodes, native extracts enriched for specific proteins are highly protective. However, recombinant forms of these proteins have failed to replicate
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