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MAK112

Arginase Activity Assay Kit

Name: Arginase Activity Assay Kit
Brand: SIGMA

sufficient for 200 colorimetric tests

동의어(들):

Arginase Test Kit

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About This Item

UNSPSC 코드:

12161503

NACRES:

NA.84

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차이점 표시

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이 품목	MRCPRT010	MRCF0R100	MRCF0R100ET
MRCF0R030 Microcon^® Centrifugal Filters	MRCPRT010 Microcon^® Centrifugal Filters	MRCF0R100 Microcon^® DNA Fast Flow Centrifugal Filters	MRCF0R100ET Microcon^® DNA Fast Flow Centrifugal Filters
material Ultracel^® regenerated cellulose membrane (low binding), polycarbonate device top, silicone O-ring (medical-grade), polyacetal base (membrane support), polypropylene tube (for filtrate/concentrate)	material Ultracel^® regenerated cellulose membrane (low binding), polyacetal base (membrane support), polycarbonate device top, polypropylene tube (for filtrate/concentrate), silicone O-ring (medical-grade)	material Ultracel^® regenerated cellulose membrane (low binding), polyacetal base (membrane support), polycarbonate device top, polypropylene tube (for filtrate/concentrate), silicone O-ring (medical-grade)	material Ultracel^® regenerated cellulose membrane (low binding), polyacetal base (membrane support), polycarbonate device top, polypropylene tube (for filtrate/concentrate), silicone O-ring (medical-grade, dual cycle ethylene oxide (EtO) treated)
pore size 30 kDa NMWCO	pore size 10 kDa NMWCO	pore size -	pore size -
manufacturer/tradename Microcon^®	manufacturer/tradename Microcon^®	manufacturer/tradename Microcon^®	manufacturer/tradename Microcon^®
parameter 0.5 mL sample volume	parameter 0.5 mL sample volume	parameter 0.5 mL sample volume	parameter 0.5 mL sample volume
sterility non-sterile	sterility non-sterile	sterility non-sterile	sterility non-sterile
feature holdup volume> 10 μL	feature holdup volume> 10 μL	feature holdup volume> 10 μL	feature holdup volume> 10 μL

일반 설명

Arginase is a manganese-containing enzyme that catalyzes the conversion of arginine to urea and ornithine.[1] Two isoforms of arginase are present in most mammals which differ in their tissue distribution and subcellular localization. Arginase I is a cytoplasmic protein predominantly expressed in the liver[2][3] where it catalyzes the fifth and final step of the Urea Cycle. Arginase II is a mitochondrial protein with broader tissue distribution whose function may include nitric oxide and polyamine metabolism. Decreased activity or expression of Arginase I results in the autosomal recessive disorder hyperarginemia.[2][3] Increased serum Arginase activity is implicated in hepatic injury and in certain pathological conditions such as cancer. Arginase also participates in multiple inflammatory reactions in the immune system, such as macrophage-mediated cytotoxicity.[1]

애플리케이션

Arginase Activity Assay Kit has been used to assess the activity of arginase.[4][5][6]

특징 및 장점

Compatible with high-throughput handling systems.

적합성

Suitable for the detection of arginase activity in enzyme preparations, serum, plasma, tissue culture, and similar samples. Suitable for studying the effects of drugs on arginase activity.

원리

In this assay, arginase catalyzes the conversion of arginine to urea and ornithine. The urea produced specifically reacts with the substrate to generate a colored product, proportional to the arginase activity present.

픽토그램

GHS08,GHS05

신호어

Danger

유해 및 위험 성명서

H290,H314,H360FD,H412

예방조치 성명서

P202 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1A

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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주요 문서

Arginase Activity Assay Kit

sufficient for 200 colorimetric tests

About This Item

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