P3556

L-α-Phosphatidylcholine

egg yolk, Type XVI-E, ≥99% (TLC), lyophilized powder

• 동의어(들): 1,2-Diacyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, L-α-Lecithin, Azolectin, PC
• CAS Number: 8002-43-5
• Beilstein: 5209585
• EC Number: 232-307-2
• UNSPSC 코드: 51321705
• NACRES: NA.25

속성

• 생물학적 소스: egg yolk
• Quality Level: 200
• 유형: Type XVI-E
• 분석: ≥99% (TLC)
• 양식: lyophilized powder
• 작용기: phospholipid
• 지질 유형: phosphoglycerides
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: [P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C

설명

일반 설명

Phosphatidylcholine belongs to the class of glycerophoshpolipids and contains choline as the head-group.[1] Choline is attached to the glycerol of fatty acids ester-bound to backbone.[1][2] It is the major phospholipid found in eukaryotic organism.[2]

애플리케이션

L-α-Phosphatidylcholine has been used:

• to form a thin lipid film used in Kupffer cell depletion by liposome-encapsulated clodronate[3]
• as a component of assay buffer used in γ-secretase in vitro assay[4]
• in the preparation of substrate mix for its use in HPLC (high performance liquid chromatography) assay of 5-lipoxygenase enzyme activity[5]

생화학적/생리학적 작용

A major structural phospholipid in brain, comprising approx. 15% of total lipid; primarily localized to gray matter.

It also acts as a source of lipid messengers/ bioactive lipids including: lysophosphatidylcholine, diacylglycerol, phosphatidic acid, lysophosphatidylcholine, arachidonic acid and platelet activating factor.[6] Phosphatidylcholine is produced in the liver by the CDP-choline (cytidine diphosphocholine) pathway.[7]

포장

Packaged under Argon

제조 메모

Prepared by a modification of the procedure of Singleton, W.S., et al., J. Am. Oil Chem. Soc., 42, 53 (1965).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)