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MilliporeSigma
모든 사진(4)

주요 문서

S2500

Sigma-Aldrich

Scopoletin

≥99%

동의어(들):

6-Methoxyumbelliferone, 6-Methylesculetin, 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one, 7-Hydroxy-6-methoxycoumarin, Buxuletin, Chrysatropic acid, Escopoletin, Esculetin-6-methyl ether, Gelseminic acid, Murrayetin

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About This Item

실험식(Hill 표기법):
C10H8O4
CAS Number:
Molecular Weight:
192.17
Beilstein:
156296
EC Number:
MDL number:
UNSPSC 코드:
12171501
PubChem Substance ID:
NACRES:
NA.28

가격 및 재고 정보를 현재 이용할 수 없음

분석

≥99%

mp

203-205 °C (lit.)

SMILES string

COc1cc2C=CC(=O)Oc2cc1O

InChI

1S/C10H8O4/c1-13-9-4-6-2-3-10(12)14-8(6)5-7(9)11/h2-5,11H,1H3

InChI key

RODXRVNMMDRFIK-UHFFFAOYSA-N

유전자 정보

human ... ACHE(43)

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애플리케이션

  • Production of Polyphenolic Natural Products by Bract-Derived Tissue Cultures of Three Medicinal Tilia spp.: A Comparative Untargeted Metabolomics Study.: This study investigates the production of polyphenolic compounds, including scopoletin, in tissue cultures derived from the bracts of three medicinal Tilia species. The research highlights the potential of these cultures in producing valuable natural products (Szűcs et al., 2024).

생화학적/생리학적 작용

Dye that can be used to detect the release of reactive oxygen species during the oxidative burst; peroxynitrite scavenger; acetylcholinesterase inhibitor.
Scopoletin significantly increases activity of lipoprotein lipase in adipocytes by promoting transcription of the LPL gene. It also partially reverses inhibition of LPL by TNF-α.[1]

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Ae Ra Kim et al.
Phytotherapy research : PTR, 18(1), 1-7 (2004-01-30)
Peroxynitrite (ONOO(-)) is one of cytotoxic species produced by the reaction between superoxide (*O(2) (-)) and nitric oxide (NO). The main aim of this study was to identify ONOO(-) scavenging constituents from herbs. Methanolic extracts derived from one hundred thirty
Shakti Deep Pachauri et al.
Journal of ethnopharmacology, 139(1), 34-41 (2011-11-24)
Noni (Morinda citrifolia L.) is widely used for different illnesses including CNS disorders. Recently Noni has been reported to prevent amyloid beta induced memory impairment in mice. However, the influence of Noni on cholinergic system has not been explored so
J T Corbett
Journal of biochemical and biophysical methods, 18(4), 297-307 (1989-06-01)
Scopoletin, 7-hydroxy-6-methoxy-2H-1-benzopyran-2-one, a naturally occurring component in cotton leaf and citrus peel is a fluorescent substrate for peroxidase which has been used by many investigators for the determination of hydrogen peroxide concentration. The technical details of these investigations are application-specific
Kamal Massoud et al.
Plant physiology, 159(1), 286-298 (2012-03-13)
Phosphite (Phi), a phloem-mobile oxyanion of phosphorous acid (H(3)PO(3)), protects plants against diseases caused by oomycetes. Its mode of action is unclear, as evidence indicates both direct antibiotic effects on pathogens as well as inhibition through enhanced plant defense responses
Wukun Liu et al.
Bioorganic & medicinal chemistry letters, 22(15), 5008-5012 (2012-07-07)
Twenty scopoletin derivatives were developed by a systematic combinatorial chemical approach and their chemical structures were confirmed by MS, IR, (1)H NMR spectra and elemental analysis. Primary screening against mammary (MCF-7 and MDA-MB 231) and colon (HT-29) carcinoma cells indicated

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