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Merck
모든 사진(1)

문서

SML0032

Sigma-Aldrich

Triacetyl resveratrol

≥98% (HPLC)

동의어(들):

3,5,4′-Tri-O-acetylresveratrol, 5-[(1E)-2-[4-(acetyloxy)phenyl]ethenyl]-1,3-Benzenediol-1,3-diacetate

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About This Item

실험식(Hill 표기법):
C20H18O6
CAS Number:
Molecular Weight:
354.35
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.25

분석

≥98% (HPLC)

형태

powder

저장 조건

protect from light

색상

white to tan

solubility

DMSO: ≥18 mg/mL

응용 분야

metabolomics
vitamins, nutraceuticals, and natural products

저장 온도

room temp

SMILES string

CC(=O)Oc1ccc(cc1)\C=C\c2cc(OC(C)=O)cc(OC(C)=O)c2

InChI

1S/C20H18O6/c1-13(21)24-18-8-6-16(7-9-18)4-5-17-10-19(25-14(2)22)12-20(11-17)26-15(3)23/h4-12H,1-3H3/b5-4+

InChI key

PDAYUJSOJIMKIS-SNAWJCMRSA-N

일반 설명

Resveratrol (RSV) is a natural polyphenolic antioxidant.

생화학적/생리학적 작용

Resveratrol prodrug. SIRT inhibitor
Resveratrol (RSV) plays a protective role on the nervous and cardiovascular systems. It is considered as a modulator of energetic metabolism as it controls glucose homeostasis in obese mice, improves fatty acid oxidation (FAO) and promotes the expression of genes that participate in mitochondrial biogenesis.
Triacetyl resveratrol displays superior bioavailability to the parent compound, resveratrol. The compound induces p53 activity and inhibits proliferation in breast and prostate tumor cell lines.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


시험 성적서(COA)

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문서 라이브러리 방문

Resveratrol induces a mitochondrial complex I dependent increase in NADH oxidation responsible for sirtuin activation in liver cells.
Desquiret-Dumas V, et al.
The Journal of Biological Chemistry, 2013 (2013)
Liqiong Ding et al.
Biochemical pharmacology, 171, 113691-113691 (2019-11-11)
Resveratrol is a natural compound found in many plant species that has broad therapeutic benefits. Here, we investigated the effects of resveratrol on the replication of HSV-2. We found that resveratrol accelerated replication of HSV-2 and increased release of progeny
Tammy R Dugas et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 107(3), 646-651 (2018-08-10)
Peripheral artery disease is a cardiovascular disease characterized by a narrowing of arteries that supply blood to the extremities, particularly, the legs. When surgical intervention is warranted, the primary approach is balloon angioplasty. Drug coated balloons (DCB) designed to release
Xiaoyun Zeng et al.
Journal of agricultural and food chemistry, 65(22), 4384-4394 (2017-05-05)
The persistence of latent HIV reservoirs presents a significant challenge to viral eradication. Effective latency reversing agents (LRAs) based on "shock and kill" strategy are urgently needed. The natural phytoalexin resveratrol has been demonstrated to enhance HIV gene expression, although
Hyeanjeong Jeong et al.
International journal of molecular sciences, 20(17) (2019-09-05)
Epigenetic remodeling via histone acetylation has become a popular therapeutic strategy to treat Alzheimer's disease (AD). In particular, histone deacetylase (HDAC) inhibitors including M344 and SAHA have been elucidated to be new drug candidates for AD, improving cognitive abilities impaired

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