MilliporeSigma
All Photos(1)

Documents

554325

Sigma-Aldrich

Resveratrol

A phenolic product found in both grape skins and wines.

Sign Into View Organizational & Contract Pricing

Synonym(s):
Resveratrol, trans-3,4ʹ,5-Trihydroxystilbene
Empirical Formula (Hill Notation):
C14H12O3
CAS Number:
Molecular Weight:
228.24
MDL number:

Quality Level

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

off-white

solubility

DMSO: 50 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+

InChI key

LUKBXSAWLPMMSZ-OWOJBTEDSA-N

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
76511PHR22011602105
vibrant-m

554325

Resveratrol

vibrant-m

76511

Resveratrol

vibrant-m

PHR2201

Trans-Resveratrol

vibrant-m

1602105

trans-Resveratrol

assay

≥98% (HPLC)

assay

-

assay

-

assay

-

Quality Level

100

Quality Level

300

Quality Level

300

Quality Level

-

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

manufacturer/tradename

-

manufacturer/tradename

USP

solubility

DMSO: 50 mg/mL

solubility

-

solubility

-

solubility

-

shipped in

ambient

shipped in

-

shipped in

-

shipped in

-

General description

A phenolic product found in both grape skin and wines. Has anti-fungal, anti-tumor and antioxidative properties. A specific inhibitor of cyclooxygenase-1 (COX-1; ED50 = 15 µM). Also inhibits the hydroxyperoxidase activity of COX-1 (ED50 = 3.7 µM). Inhibits phorbol ester-induced free radical formation in HL-60 cells (ED50 = 27 µM) and acts as an anti-mutagenic agent (ED50 = 15 µM) in TM677 cells treated with DMBA. Also selectively inhibits P450 1A1. Reported to activate sirtuins and promote the survival of eukaryotic cells.
A phenolic product found in both grape skins and wines. Has antifungal, antitumor, and antioxidative properties. A specific inhibitor of cyclooxygenase-1 (COX-1; ED50 = 15 µM). Also inhibits the hydroxyperoxidase activity of COX-1 (ED50 = 3.7 µM). Strongly inhibits insoluble transthyretin (TTR) amyloid fibril formation. Inhibits phorbol ester-induced free radical formation in HL-60 cells (ED50 = 27 µM) and acts as an anti-mutagenic agent (ED50 = 15 µM) in TM677 cells treated with DMBA. Also a selective inhibitor of P450 1A1. Reported to activate sirtuins and promote the survival of eukaryotic cells.

Biochem/physiol Actions

Cell permeable: no
ED50 = 15 µM against COX-1
Primary Target
COX-1
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Howitz, K.T., et al. 2003. Nature425, 191.
Lin, H.Y., et al. 2002. J. Urol.168, 748.
Klabunde, T., et al. 2000. Nat. Struct. Biol.7, 312.
Chun, Y.J., et al. 1999. Biochem. Biophys. Res. Commun.262, 20.
Jang, M., et al. 1997. Science 275, 218.
Chen, C.K., et al. 1996. Gen. Pharmacol.27, 363.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

392.0 °F - closed cup - (External MSDS)

flash_point_c

> 200.0 °C - closed cup - (External MSDS)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 8

1 of 8

Melatonin A hormone that has been postulated as the mediator of photo-induced anti-gonadotropic activity in photoperiodic mammals.

Sigma-Aldrich

444300

Melatonin

4-Bromo-Resveratrol ≥98% (HPLC)

Sigma-Aldrich

SML1078

4-Bromo-Resveratrol

Icariin ≥94% (HPLC)

Sigma-Aldrich

I1286

Icariin

SRT1720 SRT1720, CAS 925434-55-5, is a cell-permeable inhibitor of the mitochondrial SIRT3. Inhibition is AceCS2-competitive (Ki = 0.56 µM; Km = 2.44 µM), but NAD+-uncompetitive (Ki = 0.34 µM; Km = 280 µM).

Sigma-Aldrich

567860

SRT1720

Polydatin ≥95% (HPLC)

Sigma-Aldrich

15721

Polydatin

Eun Ji Lee et al.
Antioxidants (Basel, Switzerland), 11(6) (2022-06-25)
Emerging evidence shows that peroxisome proliferator-activated receptor delta (PPARδ) plays a pivotal role in cellular aging. However, its function in retinal disease processes such as hyperglycemia-associated diabetic retinopathy is unclear. Here, we demonstrate that PPARδ inhibits premature senescence of retinal
Elisa Franzi et al.
International journal of molecular sciences, 24(20) (2023-10-28)
Influenza virus is one of the main causes of respiratory infections worldwide. Despite the availability of seasonal vaccines and antivirals, influenza virus infections cause an important health and economic burden. Therefore, the need to identify alternative antiviral strategies persists. In
Oluwamolakun Bankole et al.
International journal of molecular sciences, 23(3) (2022-02-16)
Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder. There is no cure and current treatments fail to slow the progression of the disease. Epigenetic modulation in the acetylation state of NF-kB RelA and the histone 3 (H3) protein
Paulina Borkowska et al.
Life (Basel, Switzerland), 12(9) (2022-09-24)
The main problem with using MSC (mesenchymal stem cells) to treat the deficient diseases of the central nervous system is the low cell survival rate after the transplant procedure and their low ability to spontaneously differentiate into functional neurons. The
Taekyu Ha et al.
Molecular carcinogenesis, 58(6), 922-932 (2019-01-25)
Epithelial specific ETS-1 (ESE-1) belongs to the E26 transformation-specific transcription factor superfamily and is of great interest as a potential target for managing several types of cancer. Despite its clinical significance, the documented effects of ESE-1 on cancer development and

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service